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2019冠状病毒病大流行期间的骨折治疗:一项系统评价

Fracture management during COVID-19 pandemic: A systematic review.

作者信息

Kumar Jain Vijay, Lal Hitesh, Kumar Patralekh Mohit, Vaishya Raju

机构信息

Department of Orthopaedics, Atal Bihari Vajpayee Institute of Medical Sciences, Dr Ram Manohar Lohia Hospital, New Delhi, 110001, India.

Sports Injury Centre, Vardhman Mahavir Medical College& Safdarjung Hospital, New Delhi, 110029, India.

出版信息

J Clin Orthop Trauma. 2020 Jul;11(Suppl 4):S431-S441. doi: 10.1016/j.jcot.2020.06.035. Epub 2020 Jun 30.

Abstract

PURPOSE

The COVID-19 pandemic has affected orthopedic practices worldwide. Few studies focusing on epidemiology and management of fractures in COVID-19 patients have been published. We conducted a systematic review to evaluate the fracture types, presentation, treatment, complications, and early outcomes of fractures occurring amidst COVID-19 pandemic.

METHODS

A systematic review of the all published papers was conducted with a comprehensive search of PubMed, Google Scholar, Scopus, and Cochrane Library database using keywords 'COVID-19', 'Coronavirus', 'trauma∗'and 'fracture' from January-April 2020.

RESULTS

The searches yielded a total of ten studies with 112 Patients who were positive for COVID-19 associated with fractures was performed for six studies, reporting data separately for 44 patients with COVID 19 and an associated fracture. A diagnosis of COVID 19 was made on the basis of positive Computed Tomography scan in 39 patients and 30 patients had a positive Reverse Transcription-Polymerase Chain Reaction test. Overall, there were 29 proximal femoral fractures, 8 spine fractures, 7 fractures of the other bones. The fractures were treated surgically in 30 cases (68.18%) and the remaining 14 cases (31.82%) were managed conservatively. There were 16 patients (36.36%) who died, mostly due to respiratory failure with a median age of 82 years.

CONCLUSION

COVID-19 has led to a significant reduction in a load of fracture patients globally, though the incidence of fragility fractures continues to be unaffected. There is a significantly higher risk of mortality in elderly patients with fractures and hence they should only be operated in a facility with a robust intensive care. Conservative treatment should be adopted as far as possible in non-obligatory fractures and in lesser equipped centers. Surgery in patients with proximal femur fragility fractures when judiciously selected did result in improvement in respiratory status. Reorganizing medical services is vital to deliver effective fracture care and also mitigate disease transmission.

摘要

目的

新型冠状病毒肺炎(COVID-19)大流行已影响到全球的骨科医疗实践。很少有关于COVID-19患者骨折的流行病学和治疗的研究发表。我们进行了一项系统评价,以评估在COVID-19大流行期间发生的骨折的类型、表现、治疗、并发症和早期结果。

方法

对所有已发表的论文进行系统评价,于2020年1月至4月使用关键词“COVID-19”、“冠状病毒”、“创伤*”和“骨折”对PubMed、谷歌学术、Scopus和Cochrane图书馆数据库进行全面检索。

结果

检索共得到10项研究,其中6项研究对112例COVID-19阳性且伴有骨折的患者进行了分析,分别报告了44例COVID-19合并骨折患者的数据。39例患者根据计算机断层扫描阳性诊断为COVID-19,30例患者逆转录-聚合酶链反应检测呈阳性。总体而言,有29例股骨近端骨折、8例脊柱骨折、7例其他部位骨折。30例(68.18%)骨折患者接受了手术治疗,其余14例(31.82%)采用保守治疗。16例(36.36%)患者死亡,主要死于呼吸衰竭,中位年龄为82岁。

结论

COVID-19导致全球骨折患者数量显著减少,尽管脆性骨折的发生率仍未受影响。骨折老年患者的死亡风险显著更高,因此他们应仅在具备强大重症监护设施的机构接受手术。对于非必要骨折和设备较差的中心,应尽可能采用保守治疗。谨慎选择股骨近端脆性骨折患者进行手术确实可改善呼吸状况。重组医疗服务对于提供有效的骨折护理以及减少疾病传播至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e5f/7394814/55c995e71c3a/gr1.jpg

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