Breckenridge A
Department of Pharmacology and Therapeutics, University of Liverpool, United Kingdom.
Am J Med. 1988 Jan 29;84(1B):36-9.
Three controversies in the treatment of hypertension are reviewed. The first involves the decision whether to treat mild hypertension. Little consensus currently exists in this area and recent trial evidence is reviewed. Second, the basis of choosing specific drugs is discussed; biochemical profiling has not been overly successful, but demographic profiling and benefit profiling are to be commended. Third, the salt controversy is reviewed. On a population basis, lowering salt intake may be beneficial.
本文综述了高血压治疗中的三个争议点。第一个争议涉及是否治疗轻度高血压的决策。目前该领域尚未达成共识,本文对近期的试验证据进行了综述。其次,讨论了选择特定药物的依据;生化特征分析并未取得太大成功,但人口统计学特征分析和获益特征分析值得称赞。第三,对盐的争议进行了综述。从人群角度来看,降低盐摄入量可能有益。