Hildebolt C F, Molnar S, Elvin-Lewis M, McKee J K
Department of Diagnostic Radiology, Mallinckrodt Institute of Radiology, School of Medicine, Washington University, St. Louis, Missouri 63130.
Am J Phys Anthropol. 1988 Jan;75(1):1-14. doi: 10.1002/ajpa.1330750102.
In previous epidemiological studies, it has been suggested that geochemical factors besides fluoride may affect the prevalences of dental diseases. Our objective in this study was to determine whether the prevalences of periodontal diseases, coronal caries, and root caries for prehistoric inhabitants vary between geochemical regions of the state of Missouri. Burial sites were located on unique maps that depict geochemical variation among regions of the state. Data on dental caries and alveolar bone loss were gathered from 179 of the best preserved skeletal remains of the Late Woodland (A.D. 400-900) and Mississippian (A.D. 900-1700) periods. Mean caries scores and proportions of individuals with caries were calculated for these geochemical regions. Average alveolar bone loss was regressed on age for the individuals of these regions. Significant differences in caries and bone loss were found between several regions. These differences cannot be adequately explained by fluoride concentrations or by diet. It is suggested that geochemical factors, in addition to fluoride, may have affected the prevalences of dental diseases.
在以往的流行病学研究中，有人提出除氟之外的地球化学因素可能会影响牙科疾病的患病率。我们这项研究的目的是确定密苏里州史前居民的牙周疾病、冠龋和根龋患病率在该州不同地球化学区域之间是否存在差异。墓葬遗址位于描绘该州各区域地球化学变化的独特地图上。我们从179具保存最完好的晚期林地时期（公元400 - 900年）和密西西比时期（公元900 - 1700年）的骨骼遗骸中收集了龋齿和牙槽骨丧失的数据。计算了这些地球化学区域的平均龋齿得分和患龋个体的比例。对这些区域个体的牙槽骨平均丧失量与年龄进行了回归分析。在几个区域之间发现了龋齿和骨丧失方面的显著差异。这些差异无法通过氟浓度或饮食得到充分解释。研究表明，除氟之外，地球化学因素可能也影响了牙科疾病的患病率。
