University of Brescia and ASST Spedali Civili di Brescia, P.le Spedali Civili, 1, 25123 Brescia, Italy.
Department of Radiation Oncology, University of Brescia and ASST Spedali Civili di Brescia, Brescia, Italy.
Nucl Med Rev Cent East Eur. 2020;23(1):32-35. doi: 10.5603/NMR.2020.0004.
Radiolabelled prostate-specific membrane antigen (PSMA)-based PET/CT is a whole-body imaging technique currently performed for the detection of prostate cancer lesions. PSMA has been also demonstrated to be expressed by the neovasculature of many other solid tumours. The aim of this review is to evaluate the possible diagnostic role of radiolabelled PSMA PET/CT in breast cancer.
A comprehensive literature search of the PubMed/MEDLINE, Scopus, Embase and Cochrane Library databases was conducted to find relevant published articles about the diagnostic performance of radiolabelled PSMA PET/CT in breast cancer.
The comprehensive computer literature search revealed 652 articles. On reviewing the titles and abstracts, 640 articles were excluded because the reported data were not within the field of interest of this review. Twelve articles were selected and retrieved in full-text version; no additional study was found when screening the references of these articles. In total, 12 articles were included in the systematic review.
Further studies enrolling a wider population are needed to clarify the.
放射性标记的前列腺特异性膜抗原（PSMA）为基础的 PET/CT 是一种全身成像技术，目前用于检测前列腺癌病灶。PSMA 也被证明在许多其他实体肿瘤的新生血管中表达。本综述旨在评估放射性标记 PSMA PET/CT 在乳腺癌中的可能诊断作用。
对 PubMed/MEDLINE、Scopus、Embase 和 Cochrane Library 数据库进行了全面的文献检索，以查找关于放射性标记 PSMA PET/CT 在乳腺癌中的诊断性能的相关已发表文章。
全面的计算机文献检索显示了 652 篇文章。在审查标题和摘要时，排除了 640 篇文章，因为报告的数据不在本综述的研究领域内。选择并获取了 12 篇全文文章；在筛选这些文章的参考文献时，没有发现其他研究。总共纳入了 12 篇文章进行系统评价。
需要进一步纳入更多人群的研究来阐明其作用。
