Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Center for Psycho-oncology and Palliative Care, Nagoya City University Hospital, Nagoya, Japan.
Jpn J Clin Oncol. 2020 Dec 16;50(12):1475-1478. doi: 10.1093/jjco/hyaa143.
Patients with multiple myeloma are at risk of suicide. The study objective was to investigate the clinical risk factors of suicidal ideation among multiple myeloma patients. Consecutive inpatients with a new primary diagnosis of multiple myeloma were recruited. Patients were asked to complete the Patient Health Questionnaire-9 to measure suicidal ideation and depression. Patient demographic and biomedical characteristics (age, gender, education, marital status, employment, performance status and cancer stage) and pain and depression scores were analyzed as potential factors associated with suicidal ideation. Of the 79 patients, 10 [12.6% (95% confidence interval: 7-22)] had suicidal ideation. The results of a logistic regression analysis showed that being unmarried, less advanced cancer stage and depression were significantly associated with the presence of suicidal ideation. These findings suggest that a non-negligible proportion of patients with multiple myeloma experience suicidal ideation and that several multidimensional factors are significantly associated.
多发性骨髓瘤患者有自杀风险。本研究旨在调查多发性骨髓瘤患者自杀意念的临床危险因素。连续入组新诊断为多发性骨髓瘤的住院患者。要求患者完成患者健康问卷-9 以测量自杀意念和抑郁。分析患者人口统计学和生物医学特征（年龄、性别、教育程度、婚姻状况、就业状况、身体状况和癌症分期）以及疼痛和抑郁评分，作为与自杀意念相关的潜在因素。在 79 名患者中，有 10 名[12.6%（95%置信区间：7-22）]有自杀意念。逻辑回归分析结果表明，未婚、癌症分期较低和抑郁与自杀意念的存在显著相关。这些发现表明，相当一部分多发性骨髓瘤患者存在自杀意念，并且存在多种多维因素显著相关。
