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Using T-cell repertoire profiles as predictor in a primary mucosal melanoma.

作者信息

Chang Che-Mai, Liao Yu-Ming, Lan Gong-Yau, Chang Wei-Chiao, Yen Yun

机构信息

Ph.D. Program in Medical Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.

Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei, Taiwan.

出版信息

Clin Transl Med. 2020 Aug;10(4):e136. doi: 10.1002/ctm2.136. Epub 2020 Aug 11.

DOI:10.1002/ctm2.136
PMID:32779855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7438817/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ce/7438817/818033da21e7/CTM2-10-e136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ce/7438817/28b4a1ec5098/CTM2-10-e136-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ce/7438817/818033da21e7/CTM2-10-e136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ce/7438817/28b4a1ec5098/CTM2-10-e136-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06ce/7438817/818033da21e7/CTM2-10-e136-g002.jpg

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本文引用的文献

1
Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.从肿瘤和血液中检测和分析新抗原特异性 T 细胞群体
Cell Rep. 2019 Sep 3;28(10):2728-2738.e7. doi: 10.1016/j.celrep.2019.07.106.
2
Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies.类风湿关节炎患者接受生物治疗后的 T 细胞受体谱特征。
Dis Markers. 2019 Jul 7;2019:2364943. doi: 10.1155/2019/2364943. eCollection 2019.
3
Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors.
健康人群的纵向免疫测序揭示富含高度公共受体的持久 T 细胞受体。
BMC Immunol. 2019 Jun 21;20(1):19. doi: 10.1186/s12865-019-0300-5.
4
Radiotherapy induces responses of lung cancer to CTLA-4 blockade.放疗诱导肺癌对 CTLA-4 阻断的反应。
Nat Med. 2018 Dec;24(12):1845-1851. doi: 10.1038/s41591-018-0232-2. Epub 2018 Nov 5.
5
T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient.对血液中激活的 CD8 T 细胞进行 T 细胞受体测序，鉴定了黑色素瘤患者在 PD-1 治疗和放疗后扩增的浸润肿瘤克隆。
Cancer Immunol Immunother. 2018 Nov;67(11):1767-1776. doi: 10.1007/s00262-018-2228-7. Epub 2018 Aug 22.
6
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer.免疫识别导致转移性乳腺癌完全持久消退的体细胞突变。
Nat Med. 2018 Jun;24(6):724-730. doi: 10.1038/s41591-018-0040-8. Epub 2018 Jun 4.
7
Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.癌症中的抗程序性死亡蛋白1（Anti-PD-1）和抗细胞毒性T淋巴细胞相关蛋白4（Anti-CTLA-4）疗法：作用机制、疗效及局限性
Front Oncol. 2018 Mar 28;8:86. doi: 10.3389/fonc.2018.00086. eCollection 2018.
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The natural history and patterns of metastases from mucosal melanoma: an analysis of 706 prospectively-followed patients.黏膜黑色素瘤转移的自然史和模式：706 例前瞻性随访患者的分析。
Ann Oncol. 2017 Apr 1;28(4):868-873. doi: 10.1093/annonc/mdw694.
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Oncoimmunology. 2015 Jan 7;3(12):e968467. doi: 10.4161/21624011.2014.968467. eCollection 2014 Dec.