Center for Advanced Surgery, Baylor Scott and White Health, Dallas, TX, USA.
Department of Minimally Invasive Surgery, Baylor University Medical Center, Dallas, TX, USA.
Surg Endosc. 2021 Aug;35(8):4638-4643. doi: 10.1007/s00464-020-07890-0. Epub 2020 Aug 11.
Staple line leaks following laparoscopic sleeve gastrectomy (LSG) are associated with significant morbidity and mortality. Endoluminal techniques, including stent placement and endoluminal vacuum therapy (EVAC), have become viable options to treat these patients without the need for additional surgery. The purpose of this study was to define the conditions where certain endoscopic therapies are most likely to succeed compared to surgery.
An IRB approved prospectively maintained database was retrospectively reviewed for all patients treated for gastrointestinal leaks from July 2013 to March 2019. All patients who were treated for gastrointestinal leaks following LSG were included. Endpoints include success of leak closure and hospital-related morbidity for the patients treated solely by endoscopic only methods (EP) compared to the additional surgery group (SP).
There were 39 patients (33 females; 6 males) with a median age of 45.9 years. The EP group included 23 patients (59%), whereas SP included 16 patients (31%). On average, the SP had longer days from sentinel surgery to our hospital admission (70 vs 41), a higher percentage of previous bariatric surgery prior to sentinel LSG (50% vs 17%), and a higher readmission rates following discharge (50% vs 39%). Total length of stay was also higher in the SP compared to the EP (45.4 vs 11). Using this data, a treatment algorithm was developed to optimally treat future patients who suffer from gastrointestinal leaks following LSG.
Endoscopic therapies, such as EVAC, stent placement, internal drainage, and over-the-scope clips, have a higher chance of success if performed earlier to their sentinel surgery and if patients have had no prior bariatric surgeries. Patients who require additional surgery tend to have longer hospital stays and readmission rates. Using the treatment algorithm provided can help determine when endoscopic therapies are likely to succeed.
腹腔镜袖状胃切除术(LSG)后吻合口漏与显著的发病率和死亡率相关。腔内技术,包括支架放置和腔内真空治疗(EVAC),已成为无需额外手术即可治疗这些患者的可行选择。本研究的目的是确定与手术相比,某些内镜治疗更有可能成功的情况。
对 2013 年 7 月至 2019 年 3 月期间因胃肠道漏接受治疗的所有患者的经机构审查委员会批准的前瞻性维护数据库进行回顾性分析。所有因 LSG 后胃肠道漏而接受治疗的患者均纳入研究。主要终点包括内镜治疗(EP)组与附加手术组(SP)患者漏口闭合的成功率和与住院相关的发病率。
共 39 例患者(33 例女性;6 例男性),中位年龄 45.9 岁。EP 组 23 例(59%),SP 组 16 例(31%)。SP 组从哨兵手术到我院住院的平均天数更长(70 天 vs 41 天),在哨兵 LSG 之前接受过更多的减重手术(50% vs 17%),出院后再入院率更高(50% vs 39%)。SP 组的总住院时间也明显长于 EP 组(45.4 天 vs 11 天)。根据这些数据,开发了一种治疗算法,以优化治疗未来因 LSG 后发生胃肠道漏的患者。
如果在哨兵手术前更早进行 EVAC、支架放置、内引流和内镜夹等内镜治疗,并且患者没有进行过减重手术,内镜治疗的成功率更高。需要进行额外手术的患者往往住院时间更长,再入院率更高。使用提供的治疗算法可以帮助确定何时内镜治疗可能成功。