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决定行经食管超声心动图指导下择期电复律的因素:2 个心脏病中心的经验。

Factors determining elective cardioversion preceded by transesophageal echocardiography: experiences of 2 cardiology centers.

机构信息

Department of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland

Clinic of Cardiology and Electrotherapy, Świętokrzyskie Cardiology Centre, Kielce, Poland; Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.

出版信息

Pol Arch Intern Med. 2020 Oct 29;130(10):837-843. doi: 10.20452/pamw.15546. Epub 2020 Aug 11.

Abstract

INTRODUCTION

Although guidelines endorse cardioversion after adequate non-vitamin K antagonist oral anticoagulant (NOAC) treatment without prior transesophageal echocardiography (TEE), the majority of patients still undergo this examination.

OBJECTIVES

The aim of this study was to assess factors determining the decision to perform TEE in patients with atrial fibrillation (AF) who are eligible for elective cardioversion.

PATIENTS AND METHODS

In this study, we evaluated the medical records of consecutive patients with AF who were admitted for elective cardioversion after prior NOAC treatment.

RESULTS

Of a total of 668 patients included in the study, 362 individuals (54%) underwent TEE before cardioversion. In the univariable analysis, paroxysmal AF, hypertension, coronary artery disease (CAD), thromboembolic events, a history of percutaneous coronary intervention, a history of bleeding, left ventricular ejection fraction, left ventricular end‑ diastolic diameter, a reduced dose of NOACs, hemoglobin levels, impaired renal filtration, and a high CHA2DS2‑VASc score were significant predictors of the decision to perform TEE. In the multivariable logistic regression analysis, a history of CAD, bleeding, and stroke / transient ischemic attack / thromboembolism remained independent predictors of referring a patient for TEE (odds ratio [OR], 3.92, P <0.001; OR, 7.92, P <0.001; and OR, 2.36, P = 0.02, respectively). In contrast, paroxysmal AF (OR, 0.31; P = 0.02) and hypertension (OR, 0.28; P <0.001) were indicators of refraining from TEE.

CONCLUSIONS

Transesophageal echocardiography before cardioversion was more frequently performed in patients with a history of CAD, bleeding, or thromboembolic events. Patients with paroxysmal AF and hypertension more often received cardioversion without prior TEE.

摘要

简介

尽管指南支持在充分的非维生素 K 拮抗剂口服抗凝剂(NOAC)治疗后,无需进行经食管超声心动图(TEE)即可进行电复律,但大多数患者仍需进行该检查。

目的

本研究旨在评估在适合择期电复律的房颤(AF)患者中,决定进行 TEE 的因素。

患者和方法

在这项研究中,我们评估了因先前接受 NOAC 治疗而入院接受择期电复律的连续房颤患者的病历。

结果

在研究的 668 名患者中,共有 362 名患者(54%)在电复律前进行了 TEE。在单变量分析中,阵发性 AF、高血压、冠状动脉疾病(CAD)、血栓栓塞事件、经皮冠状动脉介入治疗史、出血史、左心室射血分数、左心室舒张末期直径、NOAC 剂量减少、血红蛋白水平、肾功能受损和较高的 CHA2DS2-VASc 评分是决定进行 TEE 的显著预测因素。在多变量逻辑回归分析中,CAD 病史、出血史和卒中和/或短暂性脑缺血发作/血栓栓塞史仍然是患者进行 TEE 的独立预测因素(比值比[OR],3.92,P<0.001;OR,7.92,P<0.001;OR,2.36,P=0.02)。相反,阵发性 AF(OR,0.31;P=0.02)和高血压(OR,0.28;P<0.001)是避免进行 TEE 的指标。

结论

在有 CAD、出血或血栓栓塞史的患者中,电复律前进行 TEE 的情况更为常见。有阵发性 AF 和高血压的患者更常接受无需 TEE 的电复律。

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