Dai Xinpei, Li Qian, Aldalbahi Ali, Wang Lihua, Fan Chunhai, Liu Xiaoguo
CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 201800, China.
Bioimaging Center, Shanghai Synchrotron Radiation Facility, Zhangjiang Laboratory, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China.
Nano Lett. 2020 Aug 12;20(8):5604-5615. doi: 10.1021/acs.nanolett.0c02511. Epub 2020 Jul 30.
The bottom-up DNA-templated nanoelectronics exploits the unparalleled self-assembly properties of DNA molecules and their amenability with various types of nanomaterials. In principle, nanoelectronic devices can be bottom-up assembled with near-atomic precision, which compares favorably with well-established top-down fabrication process with nanometer precision. Over the past decade, intensive effort has been made to develop DNA-based nanoassemblies including DNA-metal, DNA-polymer, and DNA-carbon nanotube complexes. This review introduces the history of DNA-based fabrication for nanoelectronics briefly and summarizes the state-of-art advances of DNA-based nanoelectronics. In particular, the most widely applied characterization techniques to explore their unique electronic properties at the nanoscale are described and discussed, including scanning tunneling microscopy, conductive atomic force microscopy, and Kelvin probe force microscopy. We also provide a perspective on potential applications of DNA-based nanoelectronics.
自下而上的DNA模板化纳米电子学利用了DNA分子无与伦比的自组装特性及其与各种类型纳米材料的相容性。原则上，纳米电子器件可以以接近原子的精度自下而上地组装，这与成熟的具有纳米精度的自上而下制造工艺相比具有优势。在过去十年中，人们付出了巨大努力来开发基于DNA的纳米组件，包括DNA-金属、DNA-聚合物和DNA-碳纳米管复合物。本文简要介绍了基于DNA的纳米电子学制造历史，并总结了基于DNA的纳米电子学的最新进展。特别地，描述并讨论了用于在纳米尺度上探索其独特电子特性的最广泛应用的表征技术，包括扫描隧道显微镜、导电原子力显微镜和开尔文探针力显微镜。我们还对基于DNA的纳米电子学的潜在应用提供了展望。
