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SIOP PODC 适应性治疗指南:中低收入国家颅咽管瘤治疗。

SIOP PODC-adapted treatment guidelines for craniopharyngioma in low- and middle-income settings.

机构信息

Pediatric Oncology Department, King Hussein Cancer Center, Amman, Jordan.

Division of Endocrinology, Department of Pediatric Medicine, Faculty of Health Sciences, UCT, Cape Town, South Africa.

出版信息

Pediatr Blood Cancer. 2023 Nov;70(11):e28493. doi: 10.1002/pbc.28493. Epub 2020 Aug 13.

Abstract

Pediatric craniopharyngioma is a rare tumor with excellent survival but significant long-term morbidities due to the loco-regional tumor growth or secondary to its treatment. Visual impairment, panhypopituitarism, hypothalamic damage, and behavioral changes are among the main challenges. This tumor should be managed under the care of a multidisciplinary team to determine the optimum treatment within the available resources. This is particularly important for low middle-income countries where resources are variable. This report provides risk-stratified management guidelines for children diagnosed with craniopharyngioma in a resource-limited setting.

摘要

儿童颅咽管瘤是一种罕见的肿瘤,尽管患者的生存率较高,但由于肿瘤局部生长或治疗的原因,仍存在显著的长期并发症。视力障碍、全垂体功能减退、下丘脑损伤和行为改变是主要挑战之一。该肿瘤的管理需要多学科团队的参与,以在现有资源的基础上确定最佳治疗方案。对于资源有限的中低收入国家来说,这一点尤为重要。本报告为资源有限环境中诊断为颅咽管瘤的儿童提供了风险分层的管理指南。

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