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估算伊朗伊斯兰共和国东阿塞拜疆省乙型和丙型肝炎发病率。

Estimating the incidence rate of hepatitis B and C in East Azerbaijan, Islamic Republic of Iran.

机构信息

Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran.

East Azarbaijan Provincial Health Center, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran.

出版信息

East Mediterr Health J. 2020 Jul 23;26(7):803-809. doi: 10.26719/emhj.19.077.

Abstract

BACKGROUND

The World Health Organization (WHO) has aimed for a 30% reduction in hepatitis B (HBV) and hepatitis C (HCV) incidence by 2020. To achieve this goal, it is important to have updated information about trends in the hepatitis incidence rate. However, there is a lack of up-to-date data from East Azerbaijan province in the Islamic Republic of Iran.

AIMS

This study aimed to estimate the HBV and HCV incidence rate from 2011 to 2016 in East Azerbaijan, Islamic Republic of Iran.

METHODS

Hepatitis data and population data were obtained respectively from the national notifiable disease surveillance system and the national Iranian census for 2016. For quantifying the rate of changes in incidence rate from baseline, the average annual rate of reduction (AARR) was calculated. For this, the linear regression model was used for estimating the beta coefficient. SPSS V25 was used for statistical analysis.

RESULTS

Over the 6-year period, 3119 hepatitis cases in East Azerbaijan province were reported, of which 94.7% were hepatitis B. The majority of the affected individuals were 25-44 years old. HBV incidence was reduced by 12.71% annually between 2011 and 2016. However, the number of HCV patients increased during 2014-2016, and HCV incidence rate increased insignificantly (β = 0.109, P = 0.39).

CONCLUSION

There is a significant downward trend of HBV in East Azerbaijan due to mass vaccination programmes. In the case of HCV, when considering the availability of effective treatment regimens in addition to education and prevention programmes, policy-makers should focus on HCV screening and diagnosis, especially in the 25-44 age group.

摘要

背景

世界卫生组织(WHO)的目标是到 2020 年将乙型肝炎(HBV)和丙型肝炎(HCV)的发病率降低 30%。为了实现这一目标,了解肝炎发病率趋势的最新信息非常重要。然而,伊朗伊斯兰共和国东阿塞拜疆省缺乏最新数据。

目的

本研究旨在估计 2011 年至 2016 年伊朗伊斯兰共和国东阿塞拜疆的 HBV 和 HCV 发病率。

方法

从国家传染病监测系统和 2016 年全国伊朗人口普查分别获得肝炎数据和人口数据。为了量化发病率从基线变化的速率,计算了平均年减少率(AARR)。为此,使用线性回归模型估计β系数。使用 SPSS V25 进行统计分析。

结果

在 6 年期间,报告了 3119 例东阿塞拜疆省的肝炎病例,其中 94.7%为乙型肝炎。受影响的大多数人年龄在 25-44 岁之间。2011 年至 2016 年间,HBV 发病率每年降低 12.71%。然而,2014-2016 年间 HCV 患者人数增加,且 HCV 发病率增加不显著(β=0.109,P=0.39)。

结论

由于大规模疫苗接种计划,HBV 在东阿塞拜疆呈显著下降趋势。在 HCV 方面,由于除了教育和预防方案外,还有有效的治疗方案,决策者应重点关注 HCV 筛查和诊断,特别是在 25-44 岁年龄组。

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