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日间手术与住院经皮肾镜碎石术:系统评价和荟萃分析。

Day care surgery versus inpatient percutaneous nephrolithotomy: A systematic review and meta-analysis.

机构信息

Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China.

Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China.

出版信息

Int J Surg. 2020 Sep;81:132-139. doi: 10.1016/j.ijsu.2020.07.056. Epub 2020 Aug 12.

Abstract

PURPOSE

Day care percutaneous nephrolithotomy is being performed rapidly. This meta-analysis aimed to assess the safety and efficacy of PCNL as a day care surgical procedure compared to conventional inpatient PCNL.

METHODS

Randomized controlled trials and clinical controlled trials involving day care percutaneous nephrolithotomy were included by searching PubMed, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL) and EMBASE up to Jan 2020. We completed a meta-analysis to assess the two surgical procedures.

RESULTS

Four retrospective case-controlled trials, one prospective cohort study and one randomized controlled trial were included in the meta-analysis. The meta-analysis revealed that there was no significant difference between the day care PCNL and inpatient PCNL groups in the stone-free rate (OR = 1.49; 95% CI, 0.83 to 2.67; P = 0.18). The mean overall complication rates were 13.6% and 24.4% in the day care and inpatient PCNL groups, respectively (OR = 0.47; 95% CI, 0.30 to 0.72; P < 0.001). The two groups had similar readmission rates (OR = 1.73, 95% CI, 0.67 to 4.50, P = 0.26). In addition, day care PCNL was associated with a shorter operative time (WMD = -11.89 min; 95% CI, -20.37 to -3.42; P = 0.006) and shorter hospital stay (WMD = -61.01 h; 95% CI, -107.54 to -12.48; P = 0.01).

CONCLUSIONS

Our meta-analysis demonstrated that PCNL can be performed safely and efficiently in selected patients as a day care surgical procedure.

摘要

目的

日间经皮肾镜取石术的开展速度很快。本荟萃分析旨在评估 PCNL 作为日间手术与传统住院 PCNL 相比的安全性和疗效。

方法

通过检索 PubMed、Web of Science、Cochrane 中央对照试验注册库(CENTRAL)和 EMBASE,检索截至 2020 年 1 月的日间经皮肾镜取石术的随机对照试验和临床对照试验。我们进行了荟萃分析以评估这两种手术程序。

结果

荟萃分析纳入了 4 项回顾性病例对照研究、1 项前瞻性队列研究和 1 项随机对照试验。荟萃分析显示,日间经皮肾镜取石术组与住院 PCNL 组在结石清除率方面无显著差异(OR = 1.49;95%CI,0.83 至 2.67;P = 0.18)。日间经皮肾镜取石术组和住院 PCNL 组的总体并发症发生率分别为 13.6%和 24.4%(OR = 0.47;95%CI,0.30 至 0.72;P < 0.001)。两组的再入院率相似(OR = 1.73;95%CI,0.67 至 4.50;P = 0.26)。此外,日间经皮肾镜取石术与较短的手术时间(WMD = -11.89 分钟;95%CI,-20.37 至 -3.42;P = 0.006)和较短的住院时间(WMD = -61.01 小时;95%CI,-107.54 至 -12.48;P = 0.01)相关。

结论

我们的荟萃分析表明,在选择的患者中,PCNL 可以安全有效地作为日间手术进行。

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