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支架辅助弹簧圈栓塞治疗颅底脊索瘤术前涉及基底动脉夹层动脉瘤的内镜经蝶入路颅底切除术。

Stent-Assisted Coil Embolization of a Basilar Artery Dissecting Aneurysm Involved in Skull Base Chordoma Before Endoscopic Transsphenoidal Transclival Resection.

机构信息

Department of Neurosurgery, The University of Tokyo, Tokyo, Japan.

Department of Neurosurgery, The University of Tokyo, Tokyo, Japan.

出版信息

World Neurosurg. 2020 Nov;143:466-470. doi: 10.1016/j.wneu.2020.08.054. Epub 2020 Aug 11.

DOI:10.1016/j.wneu.2020.08.054
PMID:32795685
Abstract

BACKGROUND

Skull base chordomas will occasionally penetrate the clival dura mater and extend into the prepontine cistern, involving the basilar artery. Few reports have described cases of skull base chordoma accompanying a dissecting aneurysm of the basilar artery, and the treatment strategies have remained largely unknown.

CASE DESCRIPTION

A 28-year-old man was referred to our hospital with a complaint of severe headache. A skull base chordoma involving a basilar artery dissecting aneurysm was diagnosed. We initially performed endovascular surgery for the dissecting aneurysm after dual antiplatelet therapy before surgical resection of the tumor, which was successfully achieved without complications. Follow-up angiography 3 months after endovascular surgery disclosed obliteration of the dissecting aneurysm. We then stopped the dual antiplatelet therapy, and performed judicious resection using an endoscopic transclival approach. The residual tumor was treated with radiosurgery. At the last follow-up examination, the patient was stable, and the tumor remained sufficiently controlled.

CONCLUSIONS

We have reported a case of a dissecting aneurysm of the basilar artery with clival chordoma. Our findings suggest that chordoma with intradural vascular encasement has the potential to invade the vessel wall. To avoid rupture of those critical vascular structures, treatment strategies that minimize stress on the involved arteries and offer safe and sufficient surgical resection should be considered.

摘要

背景

颅底脊索瘤偶尔会穿透斜坡硬脑膜并延伸至桥前池,累及基底动脉。很少有报道描述颅底脊索瘤伴基底动脉夹层动脉瘤的病例,其治疗策略仍知之甚少。

病例描述

一名 28 岁男性因严重头痛就诊于我院。诊断为颅底脊索瘤合并基底动脉夹层动脉瘤。我们在手术切除肿瘤前先进行了双抗治疗下的血管内手术治疗夹层动脉瘤,成功完成了手术,无并发症发生。血管内手术后 3 个月的随访血管造影显示夹层动脉瘤闭塞。随后我们停止了双抗治疗,采用内镜经颅底入路进行了谨慎的肿瘤切除。残余肿瘤采用放射外科治疗。末次随访时,患者情况稳定,肿瘤得到充分控制。

结论

我们报告了一例伴有斜坡脊索瘤的基底动脉夹层动脉瘤。我们的发现表明,硬脑膜内血管包裹的脊索瘤有可能侵犯血管壁。为了避免这些关键血管结构破裂,应考虑采用能最小化受累动脉压力并提供安全且充分的手术切除的治疗策略。

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