疑似复发性多发性骨髓瘤累及心脏外骨髓，18F-FDG 显像阳性，18F-氟胆碱显像证实。

Rare Extramedullary Cardiac Involvement of Recurrent Multiple Myeloma Suspected on 18F-FDG and Confirmed on 18F-Fluorocholine.

机构信息

From the Department of Nuclear Medicine, Hôpital Tenon AP-HP & Sorbonne Université.

Department of Hematology, Hôpital Pitié Salpêtrière AP-HP & Sorbonne Université, Paris, France.

出版信息

Clin Nucl Med. 2020 Nov;45(11):916-918. doi: 10.1097/RLU.0000000000003234.

DOI:10.1097/RLU.0000000000003234

PMID:32796239

Abstract

A man experienced pain in the right hemithorax 6 months after a first-line therapy for multiple myeloma (MM). FDG PET/CT showed a large extramedullary extent in the right hemithorax, which was biopsy proven. During the second-line treatment, FDG PET/CT showed no response as well as a suspected myocardium spread, a rare extramedullary location in MM. F-Fluorocholine PET/CT and then MRI confirmed myocardium lesions. This case confirms that F-fluorocholine PET/CT is able to detect MM recurrence and may be used to complete FDG PET/CT in difficult cases such as suspicion of cardiac MM.

摘要

一名男性在接受多发性骨髓瘤（MM）一线治疗 6 个月后出现右侧胸痛。FDG PET/CT 显示右侧胸腔有大面积髓外扩展，经活检证实。在二线治疗期间，FDG PET/CT 显示无反应，疑似心肌扩散，这是 MM 中罕见的髓外部位。F-氟胆碱 PET/CT 和 MRI 随后证实了心肌病变。该病例证实 F-氟胆碱 PET/CT 能够检测 MM 复发，并可用于在疑似心脏 MM 等困难情况下补充 FDG PET/CT。