Ophthalmology Department, Ankara University Medical School, Ankara, Turkey.
Ulucanlar Training and Research Hospital, Ankara, Turkey.
Eur J Ophthalmol. 2021 Jul;31(4):1836-1843. doi: 10.1177/1120672120950932. Epub 2020 Aug 17.
To evaluate the prevalence of uveitic glaucoma (UG) in the Turkish population and investigate the primary underlying diseases.
This multicenter, cross-sectional, prospective study included patients who presented to the glaucoma units of 10 tertiary ophthalmology departments in Ankara, Turkey from 15th March to 16th May 2015 and fulfilled the criteria of UG. Patients were inspected for age, sex, medical history, best corrected visual acuity, biomicroscopic findings, intraocular pressure values, and visual field results.
During the study period, 4604 eyes of 2541 patients with glaucoma were screened and 145 eyes of 104 patients (4.1%) were identified as having UG. One hundred and thirty-four eyes (92.4%) had open-angle glaucoma and 11 eyes (7.6%) had closed-angle glaucoma. The mean patient age was 47 ± 16 (6-90) years. Idiopathic uveitis (54 eyes), Behçet's disease (26 eyes), Fuchs heterochromic cyclitis (21 eyes), Herpes Simplex virus infectious uveitis (14 eyes), and ankylosing spondylitis (six eyes) were the leading types of uveitis associated with glaucoma. Acute anterior uveitis was the most common type of uveitis diagnosed in 72 patients (105 eyes), whereas 21 patients (27 eyes) had panuveitis, eight patients (nine eyes) had intermediate uveitis, and three patients (four eyes) had posterior uveitis. The need for surgical intervention was 37.2% among all cases and the most common surgery was trabeculectomy in 45 eyes.
UG is a vision-threatening complication commonly seen in patients with uveitis. This study demonstrates the epidemiological features and underlying etiologies of UG in the Turkish population. The most common primary causes of UG were Behçet's disease and Fuchs heterochromic cyclitis.
评估土耳其人群中葡萄膜炎性青光眼（UG）的患病率，并探讨其主要潜在疾病。
本多中心、横断面、前瞻性研究纳入了 2015 年 3 月 15 日至 5 月 16 日期间在土耳其安卡拉的 10 个三级眼科部门的青光眼科就诊且符合 UG 标准的患者。对患者的年龄、性别、病史、最佳矫正视力、眼前节检查结果、眼压值和视野结果进行了检查。
在研究期间，对 2541 名青光眼患者的 4604 只眼进行了筛查，发现 104 名患者的 145 只眼（4.1%）患有 UG。其中 134 只眼（92.4%）为开角型青光眼，11 只眼（7.6%）为闭角型青光眼。患者的平均年龄为 47±16 岁（6-90 岁）。特发性葡萄膜炎（54 只眼）、贝切特病（26 只眼）、Fuchs 异色性睫状体炎（21 只眼）、单纯疱疹病毒感染性葡萄膜炎（14 只眼）和强直性脊柱炎（6 只眼）是导致青光眼的主要葡萄膜炎类型。72 名患者（105 只眼）被诊断为急性前葡萄膜炎，是最常见的葡萄膜炎类型，21 名患者（27 只眼）患有全葡萄膜炎，8 名患者（9 只眼）患有中间葡萄膜炎，3 名患者（4 只眼）患有后葡萄膜炎。所有病例中需要手术干预的比例为 37.2%，最常见的手术是 45 只眼的小梁切除术。
UG 是葡萄膜炎患者常见的致盲性并发症。本研究显示了土耳其人群中 UG 的流行病学特征和潜在病因。UG 的最常见主要病因是贝切特病和 Fuchs 异色性睫状体炎。
