Mamedov L A, Nikolaev A V, Semenova N A, Zakharov V V, Shekhter A B
Biull Eksp Biol Med. 1988 Feb;105(2):246-8.
Twenty rabbits and fourty male rats were used for the development of the autodermoplasty model: two symmetrical semilunar skin incisions, turned to one another, with 1 cm space between the ends of the arches, were made on the back of the animal. The skin with subcutaneous fat was exfoliated from above the muscular tissue in the area between the incisions. Elastic arched net-shaped fluoroplastic plate, matching to the size of the exfoliated skin graft and raising it 1.5 cm above the wound surface was introduced into the cavity emerged. As soon as any method of wound surface purification was used, the plate was removed and the the skin graft above (conditional autodermograft) was applied and fixed to the edges of the wound with 4 interrupted sutures. It was stated that the model used for testing various methods of preparing the wound surface for autodermoplasty not only decreased the duration of experiment and the number of animals employed but cut their keeping and dressing expenditures.
使用20只兔子和40只雄性大鼠建立自体皮肤移植模型：在动物背部做两个相互对称的半月形皮肤切口，切口两端之间留出1厘米的间距。将带有皮下脂肪的皮肤从切口之间区域的肌肉组织上方剥离。将与剥离的皮肤移植物大小匹配并在创面上方抬高1.5厘米的弹性拱形网状氟塑料板放入形成的腔隙中。一旦使用任何创面清洁方法，就取出该板，然后将上方的皮肤移植物（条件性自体皮片）应用于创面边缘并用4针间断缝合固定。结果表明，用于测试自体皮肤移植创面各种制备方法的该模型不仅缩短了实验持续时间和所用动物数量，还减少了动物饲养和换药费用。
