Amouzeshi Ahmad, Zarban Asghar, Yahooian Seyede Narjes, Emampour Bibi Fatemeh Shakhs
Department of Surgery, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Iran.
Department of Clinical Biochemistry, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Iran.
Gastroenterol Res Pract. 2020 Jul 27;2020:4073059. doi: 10.1155/2020/4073059. eCollection 2020.
Appendicitis is the most common cause of surgery in people under 50. In America, it causes 250,000 cases per year and about 1 million days of hospitalization.
This cross-sectional study was performed on 20 patients under appendectomy with diagnosis of acute appendicitis. The statistical population was divided into two groups, proven appendicitis in pathology and rejection of appendicitis in pathology. Then, 10 patients were assigned into each group.
A total of 20 patients were enrolled in this study, 9 of whom were female (45%) and 11 male (55%). The most common symptom was anorexia. However, there was no statistical difference between the two groups. The lowest level of serum ghrelin was 0.95 and the highest was 16.00 in the study group, which was the mean in people with appendicitis and nonappendicitis 6.24 ± 4.09 and 5.12 ± 4.85, respectively. These values were not significantly different between the two groups ( = 0.45, df = 18, = 0.65).
This conclusion may be due to the small number of cases introduced into the study, which suggests that further investigation is warranted with a larger sample size.
阑尾炎是50岁以下人群最常见的手术病因。在美国，每年有25万例阑尾炎病例，导致约100万天的住院时间。
本横断面研究对20例接受阑尾切除术且诊断为急性阑尾炎的患者进行。统计人群分为两组，病理证实为阑尾炎组和病理排除阑尾炎组。然后，每组分配10例患者。
本研究共纳入20例患者，其中9例为女性（45%），11例为男性（55%）。最常见的症状是厌食。然而，两组之间无统计学差异。研究组血清胃饥饿素的最低水平为0.95，最高水平为16.00，阑尾炎患者和非阑尾炎患者的均值分别为6.24±4.09和5.12±4.85。两组之间这些值无显著差异（P = 0.45，自由度 = 18，t = 0.65）。
这一结论可能是由于纳入研究的病例数量较少，这表明需要以更大的样本量进行进一步调查。
