Schaeffer Anthony J, Cartwright Patrick C, Lau Glen A, Ebert Mark D, Fino Nora F, Nkoy Flory L, Hess Rachel
Division of Urology, Department of Surgery, University of Utah, Salt Lake City, UT, USA.
Intermountain Pediatric Imaging SLC, UT/Department of Radiology, University of Utah, Salt Lake City, UT, USA.
Adv Urol. 2020 Jul 30;2020:2108362. doi: 10.1155/2020/2108362. eCollection 2020.
The workup and surveillance strategies for infant hydronephrosis (HN) vary, although this could be due to grade-dependent differences in imaging intensity. We aimed to describe the frequency of imaging studies for HN within the first year of life, stratified by initial HN grade, within a large regional healthcare system. . Retrospective cohort using Intermountain Healthcare Data Warehouse. Inclusion criteria: (1) birth between 1/1/2005 and 12/31/2013, (2) CPT code for HN, and (3) ultrasound (U/S) confirmed HN within four months of birth. . Grade of HN on initial postnatal U/S; number of HN-associated radiologic studies (renal U/Ss, voiding cystourethrograms (VCUGs), and diuretic renal scans); demographic and medical variables. . Sum of radiologic studies within the first year of life or prior to pyeloplasty. . Multivariate poisson regression to analyze association between the primary outcome and the initial HN grade.
Of 1,380 subjects (993 males and 387 females), 990 (72%), 230 (17%), and 160 (12%) had mild, moderate, and severe HN, respectively. Compared with those with mild HN, patients with moderate (RR: 1.57; 95% CI: 1.42-1.73) and severe (RR: 2.09; 95% CI: 1.88-2.32) HN had a significantly higher rate of imaging use over 12 months (or prior to surgery) after controlling for potential confounders.
In a large regional healthcare system, imaging use for HN is proportional to its initial grade. This suggests that within our system, clinicians treating this condition are using a risk-stratified approach to imaging.
婴儿肾积水(HN)的检查和监测策略各不相同,尽管这可能是由于成像强度的分级依赖性差异所致。我们旨在描述在一个大型区域医疗系统中,按初始HN分级分层的1岁以内HN患儿的成像检查频率。
. 使用山间医疗数据仓库进行回顾性队列研究。纳入标准:(1)2005年1月1日至2013年12月31日出生;(2)HN的现行程序编码;(3)出生后4个月内超声(U/S)确诊为HN。
. 出生后首次U/S检查时的HN分级;与HN相关的放射学检查次数(肾脏U/S、排尿性膀胱尿道造影(VCUG)和利尿肾扫描);人口统计学和医学变量。
. 1岁以内或肾盂成形术前的放射学检查总数。
. 多变量泊松回归分析主要结局与初始HN分级之间的关联。
在1380名受试者(993名男性和387名女性)中,分别有990名(72%)、230名(17%)和160名(12%)患有轻度、中度和重度HN。与轻度HN患者相比,在控制潜在混杂因素后,中度(RR:1.57;95%CI:1.42 - 1.73)和重度(RR:2.09;95%CI:1.88 - 2.32)HN患者在12个月(或手术前)内的成像检查使用率显著更高。
在一个大型区域医疗系统中,HN的成像检查使用率与其初始分级成正比。这表明在我们的系统中,治疗这种疾病的临床医生正在采用风险分层的成像方法。