Spallone Amy, Woroch Luboslav, Sweeney Keith, Seidman Roberta, Marcos Luis A
Department of Medicine, Division of Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, USA.
Department of Radiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
J Pathog. 2020 Jul 3;2020:8174240. doi: 10.1155/2020/8174240. eCollection 2020.
Neurocysticercosis (NCC), a disease caused by the larval pork tapeworm , has emerged as an important infection in the United States. In this study, we describe the spectrum of NCC infection in eastern Long Island, where there is a growing population of immigrants from endemic countries. A retrospective study was designed to identify patients diagnosed with NCC using ICD-9 and ICD-10 codes in the electronic medical records at Stony Brook University Hospital between 2005 and 2016. We identified 52 patients (56% male, median age: 35 years) diagnosed with NCC in the only tertiary medical center in Suffolk County. Twenty-five cases were reported in the last three years of the study. Forty-eight (94%) patients self-identified as Hispanic or Latino in the electronic medical record. Twenty-two (44%) and 28 (56%) patients had parenchymal and extraparenchymal lesions, respectively. Nineteen (41.3%) patients presented with seizures to the emergency department. Six patients (11.7%) had hydrocephalus, and five of them required frequent hospitalizations and neurosurgical interventions, including permanent ventriculoperitoneal shunts or temporary external ventricular drains. No deaths were reported. The minimum accumulated estimated cost of NCC hospitalizations during the study period for all patients was approximately 1.4 million United States dollars (USD). In conclusion, NCC predominantly affects young, Hispanic immigrants in Eastern Long Island, particularly in zip codes correlating to predominantly Hispanic communities. The number of cases diagnosed increased at an alarming rate during the study period. Our study suggests a growing need for screening high-risk patients and connecting patients to care in hopes of providing early intervention and treatment to avoid potentially detrimental neurological sequelae.
神经囊尾蚴病(NCC)是一种由猪带绦虫幼虫引起的疾病,在美国已成为一种重要的感染性疾病。在本研究中,我们描述了长岛东部NCC感染的情况,该地区来自流行国家的移民人口不断增加。我们设计了一项回顾性研究,以确定2005年至2016年期间在石溪大学医院电子病历中使用ICD - 9和ICD - 10编码诊断为NCC的患者。我们在萨福克郡唯一的三级医疗中心确定了52例诊断为NCC的患者(男性占56%,中位年龄:35岁)。在研究的最后三年报告了25例病例。48名(94%)患者在电子病历中自我认定为西班牙裔或拉丁裔。分别有22名(44%)和28名(56%)患者出现实质和脑外病变。19名(41.3%)患者因癫痫发作到急诊科就诊。6名患者(11.7%)患有脑积水,其中5人需要频繁住院和神经外科干预,包括永久性脑室腹腔分流术或临时性脑室外引流。未报告死亡病例。在研究期间,所有患者NCC住院的最低累计估计费用约为140万美元。总之,NCC主要影响长岛东部年轻的西班牙裔移民,特别是在与主要为西班牙裔社区相关的邮政编码区域。在研究期间,诊断出的病例数量以惊人的速度增加。我们的研究表明,越来越需要对高危患者进行筛查,并为患者提供医疗服务,以期提供早期干预和治疗,避免潜在的有害神经后遗症。