Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Graefes Arch Clin Exp Ophthalmol. 2021 Jan;259(1):213-221. doi: 10.1007/s00417-020-04883-6. Epub 2020 Aug 17.
To study the complications and surgical outcomes of cataract surgery in patients of persistent fetal vasculature (PFV) with cataract.
In this prospective study, phacoaspiration with/without intraocular lens implantation (IOL) was done in 20 children (mean age 14.2 months) with unilateral cataract with anterior (n = 6) or combined (n = 14) PFV. The rentrolental vascularized membrane was cauterized and dissected circumferentially, followed by cauterization and resection of the PFV stalk. The outcome measures included fixation preference using the CSM (central, steady, maintained) method and intraoperative and postoperative complications in an 18-month follow-up. The difference in outcomes of anterior and combined PFV, as well as aphakic and pseudophakic eyes, was studied.
CSM fixation was seen in 16 patients after 18 months. The intraocular lens was implanted in 16 eyes and 4 eyes with combined PFV were left aphakic. None of our patients had intraoperative bleeding. Visual axis obscuration was the major complication seen, requiring membranectomy in 8 children. Pupilloplasty was required with membranectomy in one eye. None of our patients developed glaucoma or retinal detachment.
Timely surgical intervention and aggressive amblyopia therapy led to good visual results in our study. Poor prognosis was seen in combined PFV, aphakia, and microphthalmia.
研究永存原始玻璃体增生症(PFV)合并白内障患者白内障手术的并发症和手术结果。
前瞻性研究中,对 20 例单侧白内障合并前部(n=6)或联合(n=14)PFV 的患儿施行超声乳化白内障吸除术联合/不联合人工晶状体植入术。对Rentrolental 血管性膜进行电凝并环形分离,然后电凝和切除 PFV 蒂。主要观察指标为 18 个月随访时使用 CSM(中心、稳定、维持)法的固视偏好和术中及术后并发症。研究了前部和联合 PFV 以及无晶状体眼和人工晶状体眼的结果差异。
18 个月后,16 例患者出现 CSM 固定。16 只眼植入人工晶状体,4 只联合 PFV 的眼保持无晶状体。术中无出血。主要并发症为视力轴遮挡,8 例患儿需行膜切除术。1 只眼行膜切除术时需行瞳孔成形术。无患儿发生青光眼或视网膜脱离。
及时的手术干预和积极的弱视治疗使我们的研究获得了良好的视力结果。联合 PFV、无晶状体和小眼球预后较差。