永存胎儿血管的临床病理研究。
A clinicopathological study of persistent fetal vasculature.
机构信息
Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Indian J Ophthalmol. 2019 Jun;67(6):785-787. doi: 10.4103/ijo.IJO_1375_18.
PURPOSE
To study the clinicopathological findings of Persistent Fetal Vasculature (PFV) in patients with congenital cataract and PFV.
METHODS
Six eyes with anterior or combined PFV with cataract underwent phacoaspiration with primary posterior capsulotomy with anterior vitrectomy with intraocular lens implantation followed by histopathological evaluation of the PFV stalk and membrane.
RESULTS
Four and two patients had combined and anterior PFV respectively. There was no postoperative hyphema, vitreous haemorrhage, glaucoma or retinal detachment in six months. Haematoxylin and eosin staining showed inflammatory cells predominantly with extramedullary hematopoeisis and vascularisation.
CONCLUSION
We recommend IOL implantation in PFV, with early and aggressive amblyopia therapy.
目的
研究先天性白内障合并永存原始玻璃体血管（PFV）患者的临床病理特征。
方法
对 6 例合并前或完全性 PFV 及白内障的患者行白内障超声乳化吸除术联合后囊膜切开及前段玻璃体切除术，并对 PFV 血管鞘及血管膜进行组织病理学评估。
结果
4 例患者为完全性 PFV，2 例为前型 PFV。6 例患者术后 6 个月内均未发生玻璃体积血、眼内出血、青光眼或视网膜脱离。苏木精-伊红（H&E）染色显示主要为炎症细胞，伴有髓外造血和血管生成。
结论
我们建议对 PFV 患者行人工晶状体植入术，并早期积极进行弱视治疗。
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