Physiology Department, Instituto Universitario del Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Clínica IMAT Oncomédica, Montería, Colombia.
Int Urol Nephrol. 2021 Mar;53(3):489-496. doi: 10.1007/s11255-020-02601-z. Epub 2020 Aug 14.
Acute kidney injury (AKI) constitutes a serious public health problem because of its very high cost and mortality rate, with an increasing incidence, phenomenon which is explained by the increasingly number of older patients suffering from several comorbidities admitted in the intensive care units. Despite the new AKI definition and classification, the use of novel AKI biomarkers and modern technologies, as an attempt to achieve an early AKI detection and treatment, and consequently to better clinical outcomes, AKI mortality particularly in ICU patients remains persistently high. In the present article, the currently accepted concepts regarding dose and time of hemodialysis and peritoneal dialysis prescription in AKI patients have been reviewed.
急性肾损伤 (AKI) 是一个严重的公共卫生问题,因为它的成本和死亡率非常高,而且发病率不断上升,这种现象可以用越来越多患有多种合并症的老年患者入住重症监护病房来解释。尽管有了新的 AKI 定义和分类,新型 AKI 生物标志物和现代技术的应用,试图实现早期 AKI 检测和治疗,从而获得更好的临床结果,但 AKI 的死亡率,特别是 ICU 患者的死亡率仍然居高不下。在本文中,我们回顾了目前关于 AKI 患者血液透析和腹膜透析处方剂量和时间的公认概念。