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用头孢他啶-阿维巴坦成功治疗一名早产儿泛耐药肺炎克雷伯菌感染:病例报告

Successful Treatment of Pandrug-resistant Klebsiella pneumoniae Infection With Ceftazidime-avibactam in a Preterm Infant: A Case Report.

作者信息

Coskun Yesim, Atici Serkan

机构信息

From the Department of Pediatrics, Bahcesehir University School of Medicine, Medical Park Goztepe Hospital, Istanbul, Turkey.

Division of Pediatric Infectious Disease, Department of Pediatrics, Okan University School of Medicine, Istanbul, Turkey.

出版信息

Pediatr Infect Dis J. 2020 Sep;39(9):854-856. doi: 10.1097/INF.0000000000002807.

Abstract

Pandrug-resistant (PDR) bacterial infections in intensive care units are emerging as a severe problem. Therefore, new antibiotic options are urgently needed for the treatment of PDR infections in pediatric age groups, especially neonates. Herein, we report a 25 days old preterm neonate successfully treated with ceftazidime-avibactam due to a urinary tract infection caused by PDR Klebsiella pneumoniae. We aimed to describe our experiences about the safety and efficacy of ceftazidime-avibactam treatment.

摘要

重症监护病房中的泛耐药(PDR)细菌感染正成为一个严重问题。因此,迫切需要新的抗生素选择来治疗儿童年龄组,尤其是新生儿的PDR感染。在此,我们报告一例25日龄的早产新生儿因泛耐药肺炎克雷伯菌引起的尿路感染而成功接受头孢他啶-阿维巴坦治疗。我们旨在描述我们关于头孢他啶-阿维巴坦治疗的安全性和有效性的经验。

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