McLaren A, Hunt R, Simpson E
MRC Mammalian Development Unit, London, U.K.
Immunology. 1988 Mar;63(3):447-9.
Previous work has established that whereas X/X mice carrying the sex-reversing chromosomal fragment Sxr are positive for the male-specific transplantation antigen, H-Y, X/X mice carrying the variant Sxr', although they too develop as phenotypic males, are H-Y negative. In this paper we show that X/XSxr' male mice do not express any male-specific antigen that can induce skin-graft rejection.
先前的研究已经证实,携带性别反转染色体片段Sxr的X/X小鼠对雄性特异性移植抗原H-Y呈阳性,而携带变异体Sxr'的X/X小鼠,尽管它们也发育为表型雄性,但却是H-Y阴性。在本文中,我们表明X/XSxr'雄性小鼠不表达任何可诱导皮肤移植排斥的雄性特异性抗原。