Woods J W
School of Medicine, University of North Carolina, Chapel Hill.
Hypertension. 1988 Mar;11(3 Pt 2):II11-5. doi: 10.1161/01.hyp.11.3_pt_2.ii11.
Oral contraceptives result in a mild elevation of blood pressure in most women and overt hypertension in about 5%. Both estrogen and progestogen are responsible for the blood pressure effect, but the mechanism is as yet unknown. The risk of cardiovascular complications is found primarily in women over 35 years of age and in those who smoke. Preparations with an estrogen content of 30 g and a progestogen content of 1 mg or less appear to be safe.
口服避孕药会使大多数女性血压轻度升高,约5%的女性会出现明显高血压。雌激素和孕激素都与血压变化有关,但其机制尚不清楚。心血管并发症风险主要见于35岁以上女性及吸烟者。雌激素含量为30微克、孕激素含量为1毫克或更低的制剂似乎是安全的。