College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Research Centre for Medical Robotics and Minimally Invasive Surgical Devices, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
ACS Appl Mater Interfaces. 2020 Sep 9;12(36):40021-40030. doi: 10.1021/acsami.0c10097. Epub 2020 Aug 26.
Superhydrophobic surfaces repel water and other liquids such as tissue fluid, blood, urine, and pus, which can open up a new avenue for the development of biomedical devices and has led to promising advances across diverse fields, including plasma separator devices, blood-repellent sensors, vascular stents, and heart valves. Here, the fabrication of superhydrophobic liquid-solid contact triboelectric nanogenerators (TENGs) and their biomedical applications as droplet sensors are reported. Triboelectrification energy can be captured and released when droplets are colliding or slipping on the superhydrophobic layer. The developed superhydrophobic TENG possesses multiple advantages in terms of simple fabrication, bendability, self-cleaning, self-adhesiveness, high sensitivity, and repellency to not only water but also a variety of solutions, including blood with a contact angle of 158.6°. As a self-powered sensor, the developed prototypes of a drainage bottle droplet sensor and a smart intravenous injection monitor based on the superhydrophobic liquid-solid contact TENG can monitor the clinical drainage operation and intravenous infusion in real time, respectively. These prototypes suggest the potential merit of this superhydrophobic liquid-solid contact TENG in clinical application, paving the way for accurately monitoring clinical drainage operations and intravenous injection or blood transfusion in the future.
超疏水表面排斥水和其他液体，如组织液、血液、尿液和脓液，这为生物医学设备的发展开辟了新途径，并在包括等离子体分离器设备、抗血液传感器、血管支架和心脏瓣膜在内的多个领域带来了有前景的进展。在这里，报告了超疏水液-固接触摩擦纳米发电机（TENG）的制造及其作为液滴传感器在生物医学中的应用。当液滴在超疏水层上碰撞或滑动时，可以捕获和释放摩擦带电能量。所开发的超疏水 TENG 具有简单制造、柔韧性、自清洁、自粘性、高灵敏度以及不仅对水而且对多种溶液（包括接触角为 158.6°的血液）的排斥性等多种优势。作为自供电传感器，基于超疏水液-固接触 TENG 的引流瓶液滴传感器和智能静脉注射监测器的原型可以分别实时监测临床引流操作和静脉输注。这些原型表明这种超疏水液-固接触 TENG 在临床应用中的潜在价值，为未来准确监测临床引流操作和静脉注射或输血铺平了道路。
