Young V L, Fernando B, Tabas M, Wells S A, Nouhan R
Division of Plastic Surgery, Washington University School of Medicine, St. Louis, MO 63110.
J Hand Surg Am. 1988 Mar;13(2):259-62. doi: 10.1016/s0363-5023(88)80061-3.
Pyoderma gangrenosum is a rare neutrophilic dermatosis seen initially as painful pustules or bullae on the skin that rapidly ulcerate and have a characteristic raised, purplish areola surrounding them. It is often associated with inflammatory bowel disease and less commonly with other systemic diseases, such as myelofibrosis, rheumatoid arthritis, and chronic active hepatitis. Pyoderma gangrenosum involving the hand is a rare entity, with only two previous cases reported in the literature. This article describes a patient with myelofibrosis in whom pyoderma gangrenosum of the hand developed after she underwent splenectomy.
坏疽性脓皮病是一种罕见的嗜中性皮病，最初表现为皮肤上疼痛的脓疱或大疱，这些脓疱或大疱会迅速溃疡，并伴有特征性的隆起、紫色晕圈。它常与炎症性肠病相关，较少与其他全身性疾病相关，如骨髓纤维化、类风湿性关节炎和慢性活动性肝炎。手部坏疽性脓皮病是一种罕见的病症，文献中仅报道过两例。本文描述了一名患有骨髓纤维化的患者，她在接受脾切除术后手部出现了坏疽性脓皮病。
