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内镜与显微镜下 I 型鼓室成形术治疗迟发性面瘫的对比研究。

Comparative Study of Endoscopic and Microscopic Type I Tympanoplasty in Terms of Delayed Facial Palsy.

机构信息

Department of Otorhinolaryngology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Department of Otorhinolaryngology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

出版信息

Otolaryngol Head Neck Surg. 2021 Mar;164(3):645-651. doi: 10.1177/0194599820945634. Epub 2020 Aug 18.

Abstract

OBJECTIVE

Delayed facial palsy is a complication of otologic surgery. Tympanoplasty is commonly employed in chronic otitis media. We compared the incidence and characteristics of delayed facial palsy and hearing restoration between endoscopic and microscopic tympanoplasty for the treatment of simple chronic otitis media.

STUDY DESIGN

Retrospective cohort study.

SETTING

Tertiary medical center.

SUBJECTS AND METHODS

We retrospectively analyzed 468 patients who underwent type I tympanoplasty from January 2009 to April 2017. Patients were divided into transcanal endoscopic ear surgery and microscopic ear surgery groups. Their epidemiological profiles were reviewed and the outcomes of tympanoplasty were analyzed. Blood sample tests for herpes simplex virus and varicella-zoster virus immunoglobulin M and immunoglobulin G were arranged in patients with delayed facial palsy.

RESULTS

Transcanal endoscopic ear surgery exhibited similar benefits to microscopic ear surgery in graft-taking rate and hearing restoration but had a shorter operation time ( < .01). Eight patients (1.71%) developed delayed facial palsy, but no statistically significant difference was observed between the 2 surgical approaches. All patients tested negative for varicella-zoster virus and herpes simplex virus immunoglobulin M and positive for immunoglobulin G of the same viruses; however, the titer did not exhibit a 4-fold increase, implying that patients did not have active viral infections.

CONCLUSION

Transcanal endoscopic ear surgery is an ideal alternative for simple tympanoplasty. The incidence of delayed facial palsy was not significantly different between the 2 approaches. Because of the favorable prognosis and the absence of direct serological evidence supporting viral reactivation, treatment with antivirals may not be required.

摘要

目的

迟发性面瘫是耳科手术的一种并发症。鼓室成形术常用于慢性中耳炎。我们比较了内镜和显微镜下鼓室成形术治疗单纯慢性中耳炎时迟发性面瘫和听力恢复的发生率和特点。

研究设计

回顾性队列研究。

地点

三级医疗中心。

受试者和方法

我们回顾性分析了 2009 年 1 月至 2017 年 4 月期间接受 I 型鼓室成形术的 468 例患者。患者分为经耳道内镜耳手术组和显微镜耳手术组。回顾了他们的流行病学特征,并分析了鼓室成形术的结果。对迟发性面瘫患者安排单纯疱疹病毒和水痘带状疱疹病毒免疫球蛋白 M 和免疫球蛋白 G 的血液样本检测。

结果

经耳道内镜耳手术在取骨率和听力恢复方面与显微镜耳手术具有相似的益处,但手术时间更短(<0.01)。8 例(1.71%)患者发生迟发性面瘫,但两种手术方法之间无统计学差异。所有患者单纯疱疹病毒和水痘带状疱疹病毒免疫球蛋白 M 检测均为阴性,免疫球蛋白 G 检测均为阳性,但滴度未呈 4 倍增加,提示患者无活动性病毒感染。

结论

经耳道内镜耳手术是单纯鼓室成形术的理想替代方法。两种方法迟发性面瘫的发生率无显著差异。由于预后良好,且无直接血清学证据支持病毒再激活,因此可能不需要抗病毒治疗。

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