梅奥黏附概率（MAP）评分可辅助预测供肾切取术后的术后肾功能。
Mayo Adhesive Probability (MAP) score of non-donated kidney aids in predicting post-operative renal function following donor nephrectomy.
机构信息
Department of Urology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA.
出版信息
BMC Urol. 2020 Aug 17;20(1):124. doi: 10.1186/s12894-020-00695-2.
BACKGROUND
To examine the association of preoperative Mayo Adhesive Probability (MAP) scores in the donor (MAP) and non-donor kidneys (MAP) with post-donation renal function.
METHODS
Three hundred thirty-one patients undergoing hand assisted laparoscopic donor nephrectomy (HALDN) were reviewed. MAP and MAP were obtained. Estimated glomerular filtration rate (eGFR) was recorded preoperatively and at 1 day, 1 month, and 6 months postoperatively.
RESULTS
Two hundred females and 131 males were evaluated with median BMI 26.4 kg/m (range 17.1-39.6) and median age 45 years (range 19-78). MAP score was 0 for 231 patients (69.8%) and > 0 for 100 patients (30.2%). MAP score was 0 for 234 patients (70.7%) and > 0 for 97 patients (29.3%). The median preoperative eGFR was 86.6 ml/min/1.73m (range 48.8-138.4). After adjusting for preoperative eGFR, BMI, ASA score, and kidney sidedness, postoperative eGFR was associated with MAP score in the non-donated kidney (p = 0.014) but not in the donated kidney (p = 0.24). Compared to donors with MAP = 0, donors with a MAP > 0, mean eGFR was - 2.33 ml/min/1.73m lower at postoperative day 1 (95% CI - 4.24 to - 0.41, p = 0.018), - 3.02 ml/min/1.73m lower at 1 month (95% CI - 5.11 to - 0.93, p = 0.005), and - 2.63 ml/min/1.73m lower at 6 months postoperatively (95% CI - 5.01 to - 0.26, p = 0.030).
CONCLUSIONS
MAP score > 0 in the non-donated kidney is associated with worse renal function in the 6 months following HALDN.
背景
研究供体（MAP）和非供体（MAP）术前梅奥黏附概率（MAP）评分与捐肾后肾功能的关系。
方法
回顾 331 例行手辅助腹腔镜供肾切除术（HALDN）的患者。获得 MAP 和 MAP。记录术前及术后 1 天、1 个月和 6 个月的估算肾小球滤过率（eGFR）。
结果
200 名女性和 131 名男性接受了评估，平均 BMI 为 26.4kg/m（范围 17.1-39.6），平均年龄为 45 岁（范围 19-78 岁）。231 例患者 MAP 评分为 0（69.8%），100 例患者 MAP 评分>0（30.2%）。234 例患者 MAP 评分为 0（70.7%），97 例患者 MAP 评分>0（29.3%）。术前 eGFR 中位数为 86.6ml/min/1.73m（范围 48.8-138.4）。在校正术前 eGFR、BMI、ASA 评分和肾脏侧别后，非供肾的 MAP 评分与术后 eGFR 相关（p=0.014），而供肾的 MAP 评分与术后 eGFR 无关（p=0.24）。与 MAP=0 的供者相比，MAP>0 的供者术后第 1 天的平均 eGFR 低 2.33ml/min/1.73m（95%CI -4.24 至 -0.41，p=0.018），第 1 个月的平均 eGFR 低 3.02ml/min/1.73m（95%CI -5.11 至 -0.93，p=0.005），术后 6 个月的平均 eGFR 低 2.63ml/min/1.73m（95%CI -5.01 至 -0.26，p=0.030）。
结论
HALDN 术后 6 个月，非供肾的 MAP 评分>0 与肾功能下降有关。
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