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宫颈滤泡树突状细胞肉瘤:病例报告。

Follicular dendritic cell sarcoma of the uterine cervix: a case report.

机构信息

Department of Obstetrics and Gynecology, Anjo Kosei Hospital, Anjo, Aichi, Japan.

Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, 65, Tsuruma-cho, Showa-ku, Nagoya, Aichi, Japan.

出版信息

BMC Womens Health. 2020 Aug 17;20(1):182. doi: 10.1186/s12905-020-01045-y.

Abstract

BACKGROUND

Follicular dendritic cell sarcoma (FDCS) is a rare mesenchymal tumor that mostly occurs in systemic lymph nodes. FDCS in the uterine cervix has not yet been reported.

CASE PRESENTATION

A 49-year-old woman was referred to our department with a cervical tumor, which was histologically suspected to be undifferentiated carcinoma. She underwent hysterectomy, salpingo-oophorectomy, and pelvic lymphadenectomy after neoadjuvant chemotherapy with paclitaxel and carboplatin. The resected specimen contained high numbers of spindle cells and was immunohistochemically confirmed to be FDCS. The tumor was completely resected and recurrence was not detected at a 16-month follow-up.

CONCLUSION

FDCS is an extremely rare malignant tumor in the uterine cervix, and an accurate diagnosis and complete resection are essential for a good prognosis.

摘要

背景

滤泡树突状细胞肉瘤(FDCS)是一种罕见的间叶组织肿瘤,主要发生在全身淋巴结。宫颈 FDCS 尚未见报道。

病例介绍

一位 49 岁女性因宫颈肿瘤就诊,组织学怀疑为未分化癌。新辅助化疗紫杉醇+卡铂后,她接受了子宫切除术、输卵管卵巢切除术和盆腔淋巴结切除术。切除标本中含有大量梭形细胞,免疫组织化学证实为 FDCS。肿瘤完全切除,16 个月随访时未发现复发。

结论

宫颈 FDCS 是一种极为罕见的恶性肿瘤,准确诊断和完全切除是良好预后的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020d/7433043/c7249f177e17/12905_2020_1045_Fig1_HTML.jpg

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