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眼排水系统房水流动的数值模拟:健康与病态情况比较。

Numerical simulation of the aqueous humor flow in the eye drainage system; a healthy and pathological condition comparison.

机构信息

Termofluids Department, Faculty of Engineering, UNAM. México City, Coyoacán, C.P. 04510, México.

Faculty of Mechanical and Electrical Engineering. Carretera Km 9 Colima-Coquimatlán, Colima, C.P. 28400, México.

出版信息

Med Eng Phys. 2020 Sep;83:82-92. doi: 10.1016/j.medengphy.2020.07.010. Epub 2020 Jul 28.

DOI:10.1016/j.medengphy.2020.07.010
PMID:32807352
Abstract

The present work describes the motion of aqueous humor through the anterior chamber and the trabecular drainage system, considering several distributions of the collector channels. The 3D computational model, implemented into the open-source software, was reconstructed from an optical coherence tomography. The model has been employed to simulate the aqueous humor dynamics considering buoyancy effects. The presence of the anterior chamber, the trabecular meshwork, and the Schlemm's canal were taken into consideration with 14 different distributions of collector channels. The influence of collector channels position on the intraocular pressure and shear stress has been analyzed, for a healthy and a glaucomatous condition. Aqueous humor velocity, pressure, temperature, wall shear stress, skin friction coefficient and Nusselt number, are presented for the different cases. The results indicate that the position of the collector channels has a strong influence on the wall shear stress on the Schlemm's canal and collector channels.

摘要

本工作描述了考虑到几种集液管分布时房水通过前房和小梁滤过系统的运动。该三维计算模型是根据光学相干断层扫描重建到开源软件中的。该模型已被用于模拟考虑浮力效应的房水动力学。考虑到前房、小梁网和施莱姆氏管,采用了 14 种不同的集液管分布来模拟房水动力学。分析了集液管位置对正常眼和青光眼眼内压和切应力的影响。给出了不同情况下房水速度、压力、温度、壁面切应力、表面摩擦系数和努塞尔数。结果表明,集液管的位置对施莱姆氏管和集液管的壁面切应力有很大影响。

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