O'Rawe Michael, Chandran Arjun S, Joshi Stuti, Simonin Alexandre, Dyke Jason M, Lee Sharon
Department of Neurosurgery, Neurosurgical Service of Western Australia, Sir Charles Gairdner Hospital, 1st Floor, G Block, Nedlands, Perth, WA, 6009, Australia.
Department of Neurosurgery, Perth Children's Hospital, Perth, WA, Australia.
Childs Nerv Syst. 2021 Apr;37(4):1381-1385. doi: 10.1007/s00381-020-04823-z. Epub 2020 Aug 17.
Subependymal giant cell astrocytoma (SEGA) is a World Health Organization (WHO) grade I tumor most commonly seen in the context of the underlying tuberous sclerosis complex (TSC). SEGA in the absence of TSC is exceedingly rare. We report the youngest known case of SEGA in the absence of genetic or phenotypic evidence of TSC with a 10-year follow-up. We discuss the literature surrounding isolated SEGA including an approach to diagnosis, management, and prognosis.
室管膜下巨细胞星形细胞瘤（SEGA）是世界卫生组织（WHO）I级肿瘤，最常见于潜在的结节性硬化症（TSC）背景下。无TSC的SEGA极为罕见。我们报告了已知最年轻的无TSC基因或表型证据的SEGA病例，并进行了10年随访。我们讨论了有关孤立性SEGA的文献，包括诊断、管理和预后方法。
