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心肌梗死后左心室游离壁破裂:捷克布拉格临床与实验医学研究所心脏中心 12 年的经验。

Post-infarction left ventricular free wall rupture: 12-years experience from the Cardiac Centre of the Institute of Clinical and Experimental Medicine in Prague, Czech Republic.

机构信息

Department of Cardiac Surgery, University Hospital Kralovske Vinohrady, Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Cardiac Centre, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.

出版信息

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Nov;165(4):408-415. doi: 10.5507/bp.2020.022. Epub 2020 Aug 18.

Abstract

BACKGROUND

Post-infarction left ventricular free wall rupture (LVFWR) is a feared and catastrophic complication of myocardial infarction that carries a high surgical and hospital mortality. Due to the rarity of this complication, little information exists on surgical treatment and outcomes. Goal and Methods. The goal of this study was to present our experience with LVFWR. We present a retrospective cohort of 19 consecutive patients who were surgically treated in the Cardiac Centre of the Institute of Clinical and Experimental Medicine in Prague between January 2006 and December 2017.

RESULTS

Thirty-day mortality was 26%. Five patients died. Four patients died in the operating theatre and one patient on the ninth postoperative day following re-rupture. Seventy-four percent of the patient cohort survived and were discharged from hospital. The median length of follow-up was 45 months (range 0.75-150). No patient died during follow-up. Median postoperative ejection fraction was 45% (range 25-65%). Angina pectoris and dyspnea were investigated during follow-up and graded according to the Canadian cardiology society (CCS) and the New York Heart Association (NYHA) classifications. Fourteen patients had CCS class I, eight patients had NYHA class I dyspnea and six patients had NYHA class II. Re-rupture occurred after hospital discharge in one patient one month after the original surgery. The patient was treated successfully by urgent surgical intervention.

CONCLUSION

LVFWR is a catastrophic and challenging complication of myocardial infarction. Good outcomes can be achieved by rapid diagnosis and urgent surgical intervention as shown by our results.

摘要

背景

心肌梗死后左心室游离壁破裂(LVFWR)是一种可怕且灾难性的并发症,其手术和住院死亡率很高。由于这种并发症罕见,因此关于手术治疗和结果的信息很少。目的和方法。本研究的目的是介绍我们在 LVFWR 方面的经验。我们回顾性分析了布拉格临床与实验医学研究所心脏中心 2006 年 1 月至 2017 年 12 月期间连续 19 例接受手术治疗的患者。结果:30 天死亡率为 26%。有 5 名患者死亡。4 名患者在手术室死亡,1 名患者在术后第 9 天因再次破裂而死亡。74%的患者存活并出院。中位随访时间为 45 个月(0.75-150 个月)。随访期间无患者死亡。术后中位射血分数为 45%(25-65%)。在随访期间调查了心绞痛和呼吸困难,并根据加拿大心脏病学会(CCS)和纽约心脏协会(NYHA)分类进行了分级。14 例患者为 CCS Ⅰ级,8 例患者为 NYHA Ⅰ级呼吸困难,6 例患者为 NYHA Ⅱ级呼吸困难。在原始手术后 1 个月,有 1 例患者在出院后再次发生破裂。该患者通过紧急手术干预成功治疗。结论:LVFWR 是心肌梗死后一种灾难性和具有挑战性的并发症。如我们的结果所示,快速诊断和紧急手术干预可以取得良好的效果。

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