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经皮经肝胆囊造瘘术在一只因胰腺炎继发肝外胆道阻塞的犬中的应用。

Percutaneous transhepatic cholecystostomy drainage in a dog with extrahepatic biliary obstruction secondary to pancreatitis.

出版信息

J Am Vet Med Assoc. 2020 Sep 1;257(5):531-536. doi: 10.2460/javma.257.5.531.

Abstract

CASE DESCRIPTION

An 8-year-old 36.3-kg (79.9-lb) spayed female Rottweiler was evaluated because of anorexia and vomiting.

CLINICAL FINDINGS

Extrahepatic biliary obstruction (EHBO) secondary to pancreatitis was suspected on the basis of results from serum biochemical analyses, CT, and cytologic examination.

TREATMENT AND OUTCOME

Only marginal improvement was observed after 24 hours of traditional medical management; therefore, novel continual biliary drainage was achieved with ultrasonographically and fluoroscopically guided placement of a percutaneous transhepatic cholecystostomy drainage (PCD) catheter. Within 24 hours after PCD catheter placement, the dog was eating regularly, had increased intestinal peristaltic sounds on abdominal auscultation, no longer required nasogastric tube feeding, and had decreased serum total bilirubin concentration (7.7 mg/dL, compared with 23.1 mg/dL preoperatively). Bile recycling was performed by administering the drained bile back to the patient through a nasogastric tube. The PCD remained in place for 5 weeks and was successfully removed after follow-up cholangiography confirmed bile duct patency.

CLINICAL RELEVANCE

Transhepatic PCD catheter placement provided fast resolution of EHBO secondary to pancreatitis in the dog of the present report. We believe that this minimally invasive, interventional procedure has the potential to decrease morbidity and death in select patients, compared with traditional surgical options, and that additional research is warranted regarding clinical use, safety, and long-term results of this procedure in veterinary patients, particularly those that have transient causes of EHBO, are too unstable to undergo more invasive biliary diversion techniques, or have biliary diseases that could benefit from palliation alone.

摘要

病例描述

一只 8 岁、36.3 公斤(79.9 磅)已绝育的雌性罗威纳犬,因厌食和呕吐而就诊。

临床发现

基于血清生化分析、CT 和细胞学检查结果,怀疑该犬患有胰腺炎继发的肝外胆管阻塞(EHBO)。

治疗和预后

在接受传统医学治疗 24 小时后,仅观察到轻微改善;因此,通过超声和透视引导,对该犬进行了经皮经肝胆囊造口术引流(PCD)导管的新式持续胆道引流。在放置 PCD 导管后 24 小时内,该犬开始正常进食,腹部听诊时肠蠕动音增强,不再需要鼻胃管喂养,血清总胆红素浓度降低(从术前的 23.1 毫克/分升降至 7.7 毫克/分升)。通过鼻胃管将引流的胆汁回输到病犬体内,实现了胆汁再循环。PCD 留置 5 周,在后续胆管造影确认胆管通畅后成功取出。

临床相关性

在本报告的犬中,经皮经肝 PCD 导管放置术快速解决了胰腺炎继发的 EHBO。我们认为,与传统手术方法相比,这种微创介入程序有可能降低发病率和死亡率,对于那些存在 EHBO 一过性病因、不稳定而无法接受更具侵袭性的胆道分流技术、或存在可能受益于姑息治疗的胆道疾病的特定患者,有必要进一步研究该程序的临床应用、安全性和长期效果。

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