Leiphart Paul, Chu Christopher, Helm Klaus
Department of Dermatology, Penn State Health Hershey Medical Center, Hershey, Pennsylvania, USA.
J Cutan Pathol. 2021 Feb;48(2):330-333. doi: 10.1111/cup.13852. Epub 2020 Sep 7.
Dermatofibromas (DF) are common skin lesions composed of a dermal proliferation of fibroblasts and histiocytes. Among the variants of DFs, adenodermatofibroma are characterized by a dense proliferation of fibroblasts and histiocytes admixed with entrapped dilated glandular structures. We report two additional cases of adenodermatofibromas, review the literature, theorize on the histopathogenesis of this variant, and suggest that there are different patterns among adenodermatofibromas, from primarily cystic to primarily glandular.
皮肤纤维瘤（DF）是由成纤维细胞和组织细胞在真皮内增生形成的常见皮肤病变。在皮肤纤维瘤的变体中，腺性皮肤纤维瘤的特征是成纤维细胞和组织细胞密集增生，并伴有被困的扩张腺管结构。我们报告另外两例腺性皮肤纤维瘤病例，回顾相关文献，对该变体的组织发病机制进行理论探讨，并提出腺性皮肤纤维瘤存在不同模式，从主要为囊性到主要为腺性。
