Qudsiya Zainab, Gupta Vikas
St Luke's Hospital
Wellness Psychiatry P.C
Precocious puberty is defined as the appearance of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. Precocious puberty is classified as either central or peripheral precocious puberty. Central precocious puberty is gonadotropin-dependent and occurs due to early activation of the hypothalamic-pituitary-gonadal axis. Peripheral precocious puberty, also known as peripheral precocious puberty, is gonadotropin-independent and occurs due to excess production of sex hormones either from the gonads, the adrenal glands, ectopic or exogenous sources. Precocious puberty is isosexual if the signs of sexual development are consistent with the phenotypic gender of the child before the earliest accepted age of sexual maturation. If the signs of sexual development are inappropriate for the patient’s gender, then it is considered contrasexual. If left untreated, peripheral precocious puberty can lead to short stature in adulthood and have psychological consequences on the individual. Therefore, early recognition and treatment of this condition are essential to reduce morbidity.
性早熟的定义为女孩在8岁前、男孩在9岁前出现第二性征。性早熟分为中枢性性早熟和外周性性早熟。中枢性性早熟是促性腺激素依赖性的，由于下丘脑 - 垂体 - 性腺轴的过早激活而发生。外周性性早熟，也称为外周性性早熟，是促性腺激素非依赖性的，由于性腺、肾上腺、异位或外源性来源的性激素过度产生而发生。如果性发育体征与儿童在最早公认的性成熟年龄之前的表型性别一致，则性早熟为同性性早熟。如果性发育体征与患者性别不相符，则被认为是异性性早熟。如果不进行治疗，外周性性早熟可导致成年后身材矮小，并对个体产生心理影响。因此，早期识别和治疗这种疾病对于降低发病率至关重要。
