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激光在胆脂瘤手术中的应用:系统评价。

Lasers in Cholesteatoma Surgery: A Systematic Review.

机构信息

Otolaryngology Department, 7318Sheffield Teaching Hospitals, Sheffield, United Kingdom.

出版信息

Ear Nose Throat J. 2021 Feb;100(1_suppl):94S-99S. doi: 10.1177/0145561320948772. Epub 2020 Aug 18.

Abstract

OBJECTIVES

The mainstay of cholesteatoma treatment is surgical and requires the removal of all squamous epithelium from the underlying normal structure. The application of laser technology in middle ear and mastoid surgery has shown promise in achieving both disease eradication and hearing preservation. This systematic review aims to include studies that have assessed the application of laser to the treatment of cholesteatoma and to review its outcomes in terms of disease eradication as well as hearing results.

METHOD

Two independent researchers conducted a systematic review of the literature on MEDLINE and Cochrane library, according to PRISMA guidance.

RESULT

The search resulted in 12 papers, reporting on 536 participants that fulfilled the inclusion criteria. The hearing results did not show that using laser surgery improved hearing in cholesteatoma surgery, but neither has the use of laser shown to deteriorate hearing. With regards to the prevention of residual/recurrent cholesteatoma, the current literature reports a residual/recurrent rate of 0% to 33%. The complication rate of facial palsy is 0.6%.

CONCLUSION

While there is certainly a role for future studies especially randomised large-cohort prospective comparative studies, the current literature suggests that laser may have a role in prevention or minimizing of residual cholesteatoma and generally have a safe hearing outcome profile.

摘要

目的

胆脂瘤治疗的主要方法是手术,需要将所有鳞状上皮从潜在的正常结构中切除。激光技术在中耳和乳突手术中的应用显示出在实现疾病根除和听力保护方面的潜力。本系统评价旨在纳入评估激光在治疗胆脂瘤中的应用的研究,并根据疾病根除和听力结果来评价其结果。

方法

根据 PRISMA 指南,两名独立研究人员对 MEDLINE 和 Cochrane 图书馆的文献进行了系统评价。

结果

搜索结果为 12 篇论文,报告了符合纳入标准的 536 名参与者。听力结果并未表明激光手术能改善胆脂瘤手术中的听力,但激光的使用也未显示听力恶化。关于预防残余/复发性胆脂瘤,目前的文献报告残余/复发性率为 0%至 33%。面瘫的并发症发生率为 0.6%。

结论

虽然未来的研究,特别是随机大样本前瞻性对照研究肯定有其作用,但目前的文献表明,激光可能在预防或最小化残余胆脂瘤方面具有作用,并且通常具有安全的听力结果。

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