Risk of traumatic intracranial haemorrhage in children with bleeding disorders.

AIM

To assess computerised tomography (CT) use and the risk of intracranial haemorrhage (ICH) in children with bleeding disorders following a head trauma.

METHODS

Design: Multicentre prospective observational study.

SETTING

10 paediatric emergency departments (ED) in Australia and New Zealand.

PATIENTS

Children <18 years with and without bleeding disorders assessed in ED following head trauma between April 2011 and November 2014.

INTERVENTIONS

Data collection of patient characteristics, management and outcomes.

MAIN OUTCOME MEASURES

Rate of CT use and frequency of ICH on CT.

RESULTS

Of 20 137 patients overall, 103 (0.5%) had a congenital or acquired bleeding disorder. CT use was higher in these patients compared with children without bleeding disorders (30.1 vs. 10.4%; rate ratio 2.91 95% CI 2.16-3.91). Only one of 31 (3.2%) children who underwent CT in the ED had an ICH. This patient rapidly deteriorated in the ED on arrival and required neurosurgery. None of the patients with bleeding disorders who did not have a CT obtained in the ED or had an initial negative CT had evidence of ICH on follow up.

CONCLUSIONS

Although children with a bleeding disorder and a head trauma more often received a CT scan in the ED, their risk of ICH seemed low and appeared associated with post-traumatic clinical findings. Selective CT use combined with observation may be cautiously considered in these children based on clinical presentation and severity of bleeding disorder.