分化型甲状腺癌放射性碘治疗后的唾液腺和泪腺功能障碍：美国头颈协会内分泌外科学组和唾液腺学组关于耳鼻喉科、眼科、核医学和内分泌学的多学科联合临床共识声明

Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology.

作者信息

Singer Michael C, Marchal Francis, Angelos Peter, Bernet Vic, Boucai Laura, Buchholzer Samanta, Burkey Brian, Eisele David, Erkul Evren, Faure Frederic, Freitag Suzanne K, Gillespie Marion Boyd, Harrell Richard Mack, Hartl Dana, Haymart Megan, Leffert Jonathan, Mandel Susan, Miller Barbra S, Morris John, Pearce Elizabeth N, Rahmati Rahmatullah, Ryan William R, Schaitkin Barry, Schlumberger Martin, Stack Brendan C, Van Nostrand Doug, Wong Ka Kit, Randolph Gregory

机构信息

Department of Otolaryngology - Head and Neck Surgery, Henry Ford Health System, Detroit, Michigan, USA.

Department of Otolaryngology - Head and Neck Surgery, Geneva University Hospital, Geneva, Switzerland.

出版信息

Head Neck. 2020 Nov;42(11):3446-3459. doi: 10.1002/hed.26417. Epub 2020 Aug 19.

DOI:10.1002/hed.26417

PMID:32812307

Abstract

BACKGROUND

Postoperative radioactive iodine (RAI) administration is widely utilized in patients with differentiated thyroid cancer. While beneficial in select patients, it is critical to recognize the potential negative sequelae of this treatment. The prevention, diagnosis, and management of the salivary and lacrimal complications of RAI exposure are addressed in this consensus statement.

METHODS

A multidisciplinary panel of experts was convened under the auspices of the American Head and Neck Society Endocrine Surgery and Salivary Gland Sections. Following a comprehensive literature review to assess the current best evidence, this group developed six relevant consensus recommendations.

RESULTS

Consensus recommendations on RAI were made in the areas of patient assessment, optimal utilization, complication prevention, and complication management.

CONCLUSION

Salivary and lacrimal complications secondary to RAI exposure are common and need to be weighed when considering its use. The recommendations included in this statement provide direction for approaches to minimize and manage these complications.

摘要