Department of Dental Medicine, Orthodontics, 6566Albert Einstein Medical Center, Philadelphia, PA, USA.
Lancaster Cleft Palate Clinic, Lancaster, PA, USA.
Cleft Palate Craniofac J. 2021 Feb;58(2):208-214. doi: 10.1177/1055665620949433. Epub 2020 Aug 19.
To compare the outcomes between 2 groups of patients with complete clefts treated with early secondary alveolar bone grafting (ABG) at 2 centers (5-7 years, orthodontic intervention) and to a third group of patients treated at one of those centers (center 1) who had received later secondary ABG (8-10 years, orthodontic intervention).
Blind retrospective analysis of cleft site radiographs using Americleft Standardized Way to Assess Grafts (SWAG) scale.
A total of 99 patients with complete clefts from 2 North American cleft/craniofacial centers.
Secondary ABG representing 2 protocols: early grafting at a mean age of 6.6 years prior to any orthodontic intervention, and later grafting at a mean age of 10.2 years following pregrafting orthodontic intervention.
Using occlusal radiographs, the SWAG scale from 0 (failed graft) to 6 (ideal) was used. Six trained, calibrated raters scored each radiograph twice, with the average of the 2 ratings used as the final score. Reliability was assessed using the weighted κ statistic. The significance of differences between groups was determined using the Kruskal-Wallis test and Dunn test for pairwise comparisons.
Inter-rater reliability of SWAG method was good (0.631). Intra-rater reliability was excellent (0.817). There was a tendency for improved total graft outcome in the early grafted group from center 1 compared to the later grafted group with improvement being significantly different in only the coronal third of the early, preorthodontic grafted group. However, the difference was not statistically significant for the graft overall.
比较 2 个中心(5-7 岁,正畸干预)接受早期二次牙槽骨移植(ABG)治疗的完全性腭裂患者组和其中一个中心(中心 1)接受晚期二次 ABG(8-10 岁,正畸干预)治疗的第 3 组患者的治疗结果,并对腭裂部位的放射影像进行盲法回顾性分析,使用 Americleft 标准评估移植物的方法(SWAG)量表。
对 2 个北美腭裂/颅面中心的 99 例完全性腭裂患者的腭裂部位放射影像进行盲法回顾性分析,采用 Americleft 标准评估移植物的方法(SWAG)量表。
来自 2 个北美腭裂/颅面中心的 99 例完全性腭裂患者。
二次 ABG 代表 2 种方案:早期移植,即在任何正畸干预之前,平均年龄为 6.6 岁;晚期移植,即在预移植正畸干预后,平均年龄为 10.2 岁。
使用咬合放射影像,SWAG 量表评分为 0(失败移植物)至 6(理想)。6 名经过培训和校准的评分者对每个放射影像进行了 2 次评分,将 2 次评分的平均值作为最终评分。采用加权κ统计量评估可靠性。采用 Kruskal-Wallis 检验和 Dunn 检验进行两两比较,确定组间差异的显著性。
SWAG 方法的组内评分者间可靠性良好(0.631)。评分者内可靠性极好(0.817)。与晚期移植组相比,中心 1 早期移植组的总体移植物效果有改善趋势,仅在早期、正畸前移植组的冠状三分之一中,这种改善有显著差异。然而,总体移植物的差异无统计学意义。