Ophthalmic Surg Lasers Imaging Retina. 2020 Aug 1;51(8):472-475. doi: 10.3928/23258160-20200804-08.
Cystoid macular edema (CME) has been reported in the neonatal period associated with preterm birth; however, its pathogenesis remains unclear and is likely multifactorial. The authors report the case of a preterm infant imaged using optical coherence tomography (OCT), which revealed severe CME that regressed after laser treatment. Because laser for retinopathy of prematurity aims to reduce vascular endothelial growth factor (VEGF) levels, this case considers the possibility of VEGF-mediated CME pathogenesis. Further, the authors provide additional evidence of the value of OCT for noninvasive visualization of the preterm retina; the modality provides an effective way to evaluate and monitor progression of CME. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:472-475.].
晶状体后纤维增生症（CME）曾有报道与早产儿出生相关；然而，其发病机制尚不清楚，可能是多因素的。作者报告了一例使用光学相干断层扫描（OCT）成像的早产儿病例，该病例显示严重的 CME，在激光治疗后消退。由于早产儿视网膜病变的激光治疗旨在降低血管内皮生长因子（VEGF）水平，因此该病例考虑了 VEGF 介导的 CME 发病机制的可能性。此外，作者还提供了 OCT 对早产儿视网膜无创可视化的额外价值的证据；该模式为评估和监测 CME 的进展提供了一种有效的方法。[眼科手术激光成像视网膜。2020;51:472-475.]。
