八十例连续的输卵管内配子移植病例。

Eighty consecutive cases of gamete intra-fallopian transfer.

作者信息

Wong P C, Ng S C, Hamilton M P, Anandakumar C, Wong Y C, Ratnam S S

机构信息

Department of Obstetrics and Gynaecology, National University Hospital, Republic of Singapore.

出版信息

Hum Reprod. 1988 Feb;3(2):231-3. doi: 10.1093/oxfordjournals.humrep.a136683.

DOI:10.1093/oxfordjournals.humrep.a136683

PMID:3281968

Abstract

Eighty patients with the main problems of unexplained infertility, oligospermia and endometriosis were treated with gamete intra-Fallopian transfer (GIFT). From 80 treatment cycles, 29 women conceived (36.3%). Of these, four were biochemical pregnancies and therefore the clinical pregnancy rate (25/80) was 31.2%. There were six sets of multiple pregnancies, a multiple pregnancy rate of 24%. Three women (12%) miscarried. The pregnancy rates in the patients with unexplained infertility, oligospermia and endometriosis were 33.3, 16.7 and 38.5%, respectively. The transfer of four oocytes appears to increase the pregnancy rate without increasing the risk of multiple pregnancy. The presence of in-vitro fertilization of excess oocytes after GIFT did not correlate with the final outcome of GIFT.

摘要

80例主要存在不明原因不孕、少精子症和子宫内膜异位症问题的患者接受了输卵管内配子移植（GIFT）治疗。在80个治疗周期中，29名女性怀孕（36.3%）。其中，4例为生化妊娠，因此临床妊娠率（25/80）为31.2%。有6例多胎妊娠，多胎妊娠率为24%。3名女性（12%）流产。不明原因不孕、少精子症和子宫内膜异位症患者的妊娠率分别为33.3%、16.7%和38.5%。移植4个卵母细胞似乎在不增加多胎妊娠风险的情况下提高了妊娠率。GIFT后多余卵母细胞的体外受精情况与GIFT的最终结果无关。