Skopichev V G, Arutiunian N A, Proĭmina F I, Savitskiĭ G A
Tsitologiia. 1988 Jan;30(1):87-92.
The normal and the pathologically changed human myometrium was cultured in the diffusion chamber implanted in the subcutaneous cellular tissue of the rat. In the absence of hormonal influence the growth of myometrium culture is only insignificant, while no myoma cell growth was found at all. Estradiol stimulates the growth and development of the myometrium culture and the myoma. A combined action of estradiol and progesterone stimulates the collagen formation.
将正常和病理改变的人子宫肌层在植入大鼠皮下细胞组织的扩散小室中培养。在没有激素影响的情况下,子宫肌层培养物的生长微不足道,而根本未发现肌瘤细胞生长。雌二醇刺激子宫肌层培养物和肌瘤的生长与发育。雌二醇和孕酮的联合作用刺激胶原蛋白形成。