Tasca A, D'Angelo A, Zattoni F, Ferrarese P, Calò L, Bui F, Cagnato P
Istituto di Urologia, Università di Padova, Italia.
Eur Urol. 1988;14(2):120-2. doi: 10.1159/000472917.
A homogeneous group of 15 patients was investigated before and after percutaneous nephrolithotomy (PCN). Creatinine and electrolyte clearances evaluated both before and during saline (NaCl 0.9%) infusion, 4-7 days after PCN remained unchanged with respect to the preoperative values. A significant decrease of urinary PGE2 was observed postoperatively both before and after extracellular volume expansion. 99mTc-DTPA renography performed 26-40 days after surgery showed a scar on the convex margin of one kidney in the area of the nephrostomy and an improved renographic curve in 5 renal units. No difference between pre- and post-PCN isotopic clearances was evident. On the basis of our results we can affirm that PCN is an efficient and safe method for the treatment of nephrolithiasis.
对15例患者组成的同质群体在经皮肾镜取石术（PCN）前后进行了调查。在PCN术后4 - 7天，在输注生理盐水（0.9%氯化钠）之前和期间评估的肌酐和电解质清除率与术前值相比保持不变。术后在细胞外液量扩充前后均观察到尿PGE2显著下降。术后26 - 40天进行的99mTc - DTPA肾造影显示，一个肾脏肾造瘘区域的凸缘有瘢痕，5个肾单位的肾造影曲线有所改善。PCN前后的同位素清除率没有明显差异。根据我们的结果，我们可以肯定PCN是治疗肾结石的一种有效且安全的方法。
