Dangli A, Guialis A, Vretou E, Sekeris C E
Biological Research Center, National Hellenic Research Foundation, Athens, Greece.
FEBS Lett. 1988 Apr 11;231(1):118-24. doi: 10.1016/0014-5793(88)80714-2.
A novel autoantibody reacting the the core polypeptides of hnRNP particles has been detected in the serum of a patient with systemic lupus erythematosus (SLE) and Sjögren's syndrome manifestations. Immunoblot analysis, using either rat liver or HeLa nuclear extracts as the antigen source, demonstrated that the autoantibody interacts with a specific subgroup of the core polypeptides of hnRNP particles, namely A2, B1 and B2, but not with A1, C1 and C2.
在一名患有系统性红斑狼疮（SLE）和干燥综合征表现的患者血清中，检测到一种与hnRNP颗粒核心多肽发生反应的新型自身抗体。以大鼠肝脏或HeLa细胞核提取物作为抗原来源进行免疫印迹分析表明，该自身抗体与hnRNP颗粒核心多肽的一个特定亚组相互作用，即A2、B1和B2，但不与A1、C1和C2相互作用。
