Lennerstrand G
Department of Ophthalmology, Karolinska Institute, Huddinge University Hospital, Sweden.
Graefes Arch Clin Exp Ophthalmol. 1988;226(2):172-4. doi: 10.1007/BF02173311.
Basic research in the field of oculomotor physiology has advanced rapidly during the last decade. The new knowledge has been largely incorporated into the research and the clinical practice of neurology and neuroophthalmology [14, 16], but the influence on strabismus research has been rather limited [15]. This presentation will point out the elements of basic research that are believed important for our understanding of concomitant strabismus. The description will concentrate on the role of different central motor factors, mainly brainstem mechanisms, in the genesis and development of infantile esotropia or convergent strabismus, i.e. strabismus with an early onset in life [8]. Strabismus of late onset seems less enigmatic, since it probably originates from abnormalities of the vergence system, particularly its coupling with accommodation.
在过去十年中,眼球运动生理学领域的基础研究进展迅速。这些新知识在很大程度上已被纳入神经病学和神经眼科学的研究及临床实践中[14, 16],但对斜视研究的影响相当有限[15]。本报告将指出基础研究中那些被认为对我们理解共同性斜视很重要的要素。描述将集中于不同中枢运动因素的作用,主要是脑干机制,在婴儿型内斜视或会聚性斜视(即生命早期发病的斜视)[8]的发生和发展中的作用。晚发性斜视似乎不那么神秘,因为它可能源于聚散系统的异常,尤其是其与调节的耦合异常。