Shaiju V S, Kumar Rajesh, Phani Debjani, Rajasekhar K V, Zacharia George, Bhasi Saju, Nair Raghuram K
Department of Radiation Physics, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
J Med Phys. 2020 Apr-Jun;45(2):66-70. doi: 10.4103/jmp.JMP_21_20. Epub 2020 Jul 20.
The present study aims to design and fabricate a novel, versatile, and cost-effective Polymethyl Methacrylate (PMMA) head phantom for the dosimetric pretreatment verification of radiotherapy (RT) treatment plans.
The head phantom designing involves slice-wise modeling of an adult head using PMMA. The phantom has provisions to hold detectors such as ionization chambers of different sizes, Gafchromic films, gel dosimeter, and optically stimulated luminescence dosimeter. For the point dose verification purpose, 15 volumetric modulated arc therapy patient plans were selected, and doses were measured using a CC13 ionization chamber. The percentage gamma passing rate was calculated for acceptance criteria 3%/3 mm and 2%/2 mm using OmniPro I'mRT film QA software, and Gafchromic EBT3 films were used for 2D planar dose verification.
Treatment planning system calculated, and the measured point doses showed a percentage deviation ranged from 0.26 to 1.92. The planar dose fluence measurements, for set acceptance criteria of 3%/3 mm and 2%/2 mm, percentages of points having gamma value <1 were in the range of 99.17 ± 0.25 to 99.88 ± 0.15 and 93.16 ± 0.38 to 98.89 ± 0.23, respectively. Measured dose verification indices were within the acceptable limit.
The dosimetric study reveals that head phantom can be used for routine pretreatment verification for the cranial RT, especially for stereotactic radiosurgery/RT as a part of patient-specific quality assurance. The presently fabricated and validated phantom is novel, versatile, and cost-effective, and many institutes can afford it.
本研究旨在设计并制造一种新型、通用且经济高效的聚甲基丙烯酸甲酯(PMMA)头部体模,用于放射治疗(RT)治疗计划的剂量学预处理验证。
头部体模设计包括使用PMMA对成人头部进行分层建模。该体模有用于放置探测器的装置,如不同尺寸的电离室、放射变色胶片、凝胶剂量计和光激励发光剂量计。为了进行点剂量验证,选择了15个容积调强弧形治疗患者计划,并使用CC13电离室测量剂量。使用OmniPro I'mRT胶片QA软件计算3%/3 mm和2%/2 mm验收标准下的伽马通过率,并用放射变色EBT3胶片进行二维平面剂量验证。
治疗计划系统计算的和测量的点剂量显示百分比偏差范围为0.26至1.92。对于3%/3 mm和2%/2 mm的设定验收标准,平面剂量注量测量中伽马值<1的点的百分比分别在99.17±0.25至99.88±0.15和93.16±0.38至98.89±0.23范围内。测量的剂量验证指标在可接受范围内。
剂量学研究表明,该头部体模可用于颅脑放疗的常规预处理验证,特别是作为患者特定质量保证的一部分用于立体定向放射外科/放疗。目前制造并验证的体模新颖、通用且经济高效,许多机构都能负担得起。