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丙烯腈-丁二烯-苯乙烯(ABS)塑料低成本组织等效体模用于 IMRT 中的验证剂量学。

Acrylonitrile Butadiene Styrene (ABS) plastic based low cost tissue equivalent phantom for verification dosimetry in IMRT.

机构信息

Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, CT&CRS, Anushaktinagar, Mumbai, India.

出版信息

J Appl Clin Med Phys. 2009 Dec 17;11(1):3030. doi: 10.1120/jacmp.v11i1.3030.

Abstract

A novel IMRT phantom was designed and fabricated using Acrylonitrile Butadiene Styrene (ABS) plastic. Physical properties of ABS plastic related to radiation interaction and dosimetry were compared with commonly available phantom materials for dose measurements in radiotherapy. The ABS IMRT phantom has provisions to hold various types of detectors such as ion chambers, radiographic/radiochromic films, TLDs, MOSFETs, and gel dosimeters. The measurements related to pre-treatment dose verification in IMRT of carcinoma prostate were carried out using ABS and Scanditronics-Wellhoffer RW3 IMRT phantoms for five different cases. Point dose data were acquired using ionization chamber and TLD discs while Gafchromic EBT and radiographic EDR2 films were used for generating 2-D dose distributions. Treatment planning system (TPS) calculated and measured doses in ABS plastic and RW3 IMRT phantom were in agreement within +/-2%. The dose values at a point in a given patient acquired using ABS and RW3 phantoms were found comparable within 1%. Fluence maps and dose distributions of these patients generated by TPS and measured in ABS IMRT phantom were also found comparable both numerically and spatially. This study indicates that ABS plastic IMRT phantom is a tissue equivalent phantom and dosimetrically it is similar to solid/plastic water IMRT phantoms. Though this material is demonstrated for IMRT dose verification but it can be used as a tissue equivalent phantom material for other dosimetry purposes in radiotherapy.

摘要

设计并制作了一种使用丙烯腈丁二烯苯乙烯(ABS)塑料的新型调强适形射束验证体模。与放射治疗中剂量测量常用的体模材料相比,ABS 塑料的辐射相互作用和剂量学相关物理特性进行了比较。ABS 调强适形射束验证体模具有用于容纳各种类型探测器的设施,例如电离室、射线照相/辐射显色胶片、TLD、MOSFET 和凝胶剂量计。使用 ABS 和 Scanditronics-Wellhoffer RW3 调强适形射束验证体模对 5 种不同情况的前列腺癌调强放射治疗进行了治疗前剂量验证测量。使用电离室和 TLD 圆盘获取点剂量数据,同时使用 Gafchromic EBT 和射线照相 EDR2 胶片生成 2-D 剂量分布。治疗计划系统(TPS)计算和测量 ABS 塑料和 RW3 调强适形射束验证体模中的剂量,结果在 +/-2%以内一致。使用 ABS 和 RW3 体模在特定患者中获得的给定点的剂量值在 1%以内具有可比性。TPS 生成的这些患者的通量图和剂量分布以及在 ABS 调强适形射束验证体模中测量的结果在数值和空间上都具有可比性。这项研究表明,ABS 塑料调强适形射束验证体模是一种组织等效体模,在剂量学方面与固体/塑料水调强适形射束验证体模相似。尽管该材料已用于调强剂量验证,但它可作为放射治疗中其他剂量学目的的组织等效体模材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d72b/5719786/3d29a80b2dfc/ACM2-11-024-g001.jpg

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