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先天性视力障碍单卵双胞胎中的多发性牙齿包涵体

Multiple Dental Inclusion in Monozygotic Twins with Congenital Visual Impairment.

作者信息

Galluccio G, Impellizzeri A, De Stefano A A, Serritella E, Guercio Monaco E

机构信息

Department of Oral and Maxillo Facial Sciences, Faculty of Medicine and Dentistry, Sapienza Università di Roma, Italy.

Department of Orthodontics, Faculty of Dentistry, University Central of Venezuela, Caracas, Venezuela.

出版信息

Case Rep Dent. 2020 Aug 6;2020:8856206. doi: 10.1155/2020/8856206. eCollection 2020.

Abstract

The study presents two monozygotic twins (MZ) with multiple impacted teeth, affecting the upper canines and lower second molars, as well as congenital aniridia. The clinical aspect of the upper canines is peculiar because of the different positions-palatal in one and buccal in the other twin. Studies reporting different scenarios of impaction in monozygotic twins can contribute more data to the debate on tooth eruption aetiology and more so in this case because of the association with a genetic panocular disease. . The patients were referred by a general dentist, who diagnosed the presence of multiple inclusions. . Both patients showed severe malocclusion, classified as grade 5 of the Index of Orthodontic Treatment Need (IOTN). The MZ showed class I malocclusion, upper and lower crowding, and impacted lower right and left second molars. A Dentascan was prescribed for the canine impaction. The impaction of the upper canine was palatal of 2.3 in one of the MZ and buccal of 1.3 in the other one. The same altered pattern of eruption of the lower second molars was identified in both twins. The proposed treatment plan contemplated orthodontic surgical recovery of the impacted elements, followed by orthodontic treatment with multibracket appliance after the extraction of the first four premolars, given the crowding entity. The use of a retraction spring action was chosen for the recovery of the lower second molars. Many aspects of the possible genetic aetiology of tooth impaction are still under discussion. The study of diseases in twins offers decisive information. Finally, the possibility that alterations in the eruptive pattern of the dental elements may be associated with other congenital problems broadens the range of investigations related to the possible aetiological causes of the inclusions in humans.

摘要

该研究报告了一对患有多颗埋伏牙的同卵双胞胎(MZ),这些埋伏牙影响上颌尖牙和下颌第二磨牙,同时还患有先天性无虹膜症。上颌尖牙的临床情况较为特殊,因为在这对双胞胎中,一颗尖牙位于腭侧,另一颗位于颊侧。报道同卵双胞胎中不同埋伏情况的研究可以为牙齿萌出病因的争论提供更多数据,在这种情况下更是如此,因为它与一种遗传性全眼疾病有关。患者由一位普通牙医转诊,该牙医诊断出存在多处埋伏。两位患者均表现出严重的错颌畸形,根据正畸治疗需求指数(IOTN)分类为5级。这对同卵双胞胎表现为I类错颌、上下牙列拥挤,以及右下和左下第二磨牙埋伏。针对尖牙埋伏情况进行了口腔锥形束计算机断层扫描(Dentascan)。在其中一名同卵双胞胎中,上颌尖牙的埋伏位置在腭侧2.3处,而在另一名双胞胎中则在颊侧1.3处。在这对双胞胎中均发现了下颌第二磨牙相同的异常萌出模式。考虑到牙列拥挤情况,拟定的治疗方案包括对埋伏牙进行正畸手术复位,然后在拔除四颗第一前磨牙后使用多托槽矫治器进行正畸治疗。对于下颌第二磨牙的复位,选择使用回缩弹簧作用。牙齿埋伏可能的遗传病因的许多方面仍在讨论中。对双胞胎疾病的研究提供了决定性信息。最后,牙齿萌出模式的改变可能与其他先天性问题相关的可能性拓宽了与人类埋伏可能病因相关调查的范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a90f/7428941/002912dca00a/CRID2020-8856206.001.jpg

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