Yeoh Cindy B, Lee Kathleen J, Tollinche Luis E
Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065.
Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14263.
Int J Clin Case Rep Rev. 2020;3(1). Epub 2020 Jul 31.
Stiff-person syndrome (SPS) is a rare disorder of the nervous system, characterized by muscle stiffness, rigidity, and painful spasms involving truncal and limb musculature that may severely limit mobility. Our case documents a 53-year-old patient with SPS and endometrial cancer who was positive for anti-GAD and paraneoplastic antibodies, who presented to our institution for robotic surgery. These patients are at high risk for prolonged hypotonia and mechanical ventilation. Our patient underwent general anesthesia without complications despite multiple comorbidities.
僵人综合征（SPS）是一种罕见的神经系统疾病，其特征为肌肉僵硬、强直以及涉及躯干和肢体肌肉组织的疼痛性痉挛，这可能会严重限制活动能力。我们的病例记录了一名53岁患有SPS和子宫内膜癌的患者，其抗谷氨酸脱羧酶抗体和副肿瘤抗体呈阳性，该患者到我们机构接受机器人手术。这些患者有发生长时间肌张力减退和机械通气的高风险。尽管有多种合并症，我们的患者仍顺利接受了全身麻醉，未出现并发症。
